Evaluation of antiplasmodial activity of extracts from endemic medicinal plants used to treat malaria in Côte d'Ivoire.

strains had been increasingly resistant to commonly used molecules including artemisinin. It is therefore urges to find new therapeutic alternatives. In this study, the antiplasmodial activity of 21 extracts obtained from seven plants of the and of the Ivorian pharmacopoeia was evaluated on the chloroquine sensitive (NF54) and multi-resistant (K1) reference strains and on clinical isolates as well. The technique used was the microtiter method based on fluorescence reading with SYBR Green. The aqueous extract of the bark of H. madagascariensis and methanolic extracts of showed the best antiplasmodial activity with IC values of 6.16 µg/mL and 7.44 µg/mL, respectively. On the other hand, extracts of showed a very moderate activity with IC values between 15 µg/mL and 50 µg/mL (5

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416013	PMC
http://dx.doi.org/10.34172/bi.2020.19	DOI Listing