The USA is witnessing an outbreak of vaping-induced lung injuries associated with the drastic rise in e-cigarette use, especially among teenagers and young adults. Our understanding of the harmful effects of these products is expanding as an increasing amount of consumers seek medical care for lung-related illnesses. The knowledge of the long-term sequelae of e-cigarette use is limited due to their novelty, but a growing association exists between use and acute lung injury. We describe a case vignette of vaping-induced lung injury to increase physician awareness and discuss the applicability of preliminary diagnostic criteria.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416831 | PMC |
| http://dx.doi.org/10.1093/omcr/omaa060 | DOI Listing |
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- Proteases, particularly neutrophil elastase, activate the epithelial sodium channel (ENaC) and contribute to dehydration in the airways, which is a concern for lung health.
- This study investigates how higher levels of proteases in the airways of vapers affect ENaC activity and hydration by exposing human bronchial epithelial cultures to fluid from non-smokers, smokers, and vapers.
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