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| http://dx.doi.org/10.1055/a-1230-0002 | DOI Listing |
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Hydroxychloroquine enhances insulin sensitivity and ameliorates abnormal lipid metabolism in obese women with polycystic ovary syndrome.
BMC Endocr Disord
January 2025
Hospital Affiliated to Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250011, China.
Background: Hydroxychloroquine (HCQ) is frequently utilized in rheumatic immune disorders and has been discovered to exert hypoglycemic effects in some obese women with polycystic ovary syndrome(PCOS), however, the precise efficacy and mechanism of action remain ambiguous.
Objective: To examine the impact of HCQ on glucose and lipid metabolism as well as sex hormone levels in obese women with PCOS.
Method: Fifty obese women with PCOS were randomly allocated into two groups: HCQ group (n = 25) and metformin (MET) group (n = 25).
Protein-losing enteropathy as the first presentation of systemic lupus erythematosus the first case reported in Palestine with systemic review.
Ann Med Surg (Lond)
December 2024
Al- Ahli Hospital, Department of Internal Medicine, Hebron, State of Palestine.
Introduction: Systemic lupus erythematosus is a chronic inflammatory disease affecting women, causing gastrointestinal issues like acute pancreatitis, esophagitis, and protein-losing enteropathy. Protein loss is uncommon, but a case study shows protein-losing enteropathy as a first sign.
Importance: Protein-losing enteropathy (PLE) is a rare gastrointestinal manifestation of SLE, often seen years before diagnosis.
"They Only Silence the Truth": COVID-19 retractions and the politicization of science.
Public Underst Sci
October 2024
Northwestern University, USA.
Retracted COVID-19 articles have circulated widely on social media. Although retractions are intended to correct the scientific record, when trust in science is low, they may instead be interpreted as evidence of censorship or simply ignored. We performed a content analysis of tweets about the two most widely shared retracted COVID-19 articles, Mehra20 and Rose21, before and after their retractions.
View Article and Find Full Text PDFHow to treat patients with thrombotic antiphospholipid syndrome in 2024?
Pol Arch Intern Med
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Antiphospholipid syndrome (APS) encompasses a range of clinical conditions, particularly thrombotic or obstetrical manifestations, associated with the presence of antiphospholipid antibodies. Managing thrombotic APS in daily clinical practice can be challenging and requires thorough risk stratification and tailored treatment strategies. Primary prophylaxis focuses on correcting the traditional thrombotic risk factors and, in certain situations, may include low‑dose aspirin and / or prophylactic anticoagulants (eg, low‑molecular‑weight heparin).
View Article and Find Full Text PDFThe (reverse) paradox of lupus anticoagulant: A case report.
Lupus
October 2024
Department of Rheumatology, Max Super Speciality Hospital, New Delhi, India.
Article Synopsis
- Systemic Lupus Erythematosus (SLE) often coexists with antiphospholipid syndrome, leading to blood clotting issues or complications in pregnancy, as illustrated by a case of a 7-year-old girl experiencing fever, bleeding, and thrombophlebitis.
- The child presented with symptoms like gum bleeding, small skin lesions, and abnormal blood coagulation tests, prompting further investigation for an autoimmune disorder.
- Ultimately, she was diagnosed with Systemic Lupus Erythematosus and Lupus Anticoagulant Hypoprothrombinemia Syndrome after confirming the presence of specific antibodies and coagulation abnormalities.
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