To discuss the clinical efficacy of low-temperature radiofrequency ablaion assisted by endoscopy for the treatment of congenital pyriform sinus fistula in infants. Clinical data of 15 patients with CPSF received the low-temperature radiofrequency ablaion assisted by endoscopy under laryngoscope were reviewed. After the operation, patients were followed up closely at different stages. All patients underwent neck color doppler ultrasound and electronic laryngoscopy, and the results were analyzed. The operation of 15 children was successfully completed without pharyngeal fistula, dysphagia, perifistula and distal fistula infection. Followup survey ranged from 3 months to 3 years and no one recurred. Low-temperature radiofrequency ablaion assisted by endoscopy is a promising method for the CPSF with less trauma, less haemorrhage and good vision. It is safe and effective for the treatment of CPSF in infants and children, and is worthy of clinical promotion.
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http://dx.doi.org/10.13201/j.issn.2096-7993.2020.05.017 | DOI Listing |
JA Clin Rep
January 2025
Department of Pain Clinic, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, Shinagawa-Ku, Tokyo, 141-8625, Japan.
Background: Bilateral trigeminal neuralgia secondary to multiple sclerosis is an extremely rare condition. When Gasserian ganglion block is performed, it is necessary to achieve reliable long-term analgesic effects while avoiding treatment-related complications.
Case Presentation: A 49-year-old male with multiple sclerosis exhibited persistent dull pain and paroxysmal electric shock-like pain in his bilateral maxillary molars and mandible.
J Magn Reson
December 2024
Oral Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Gothenburg, Sweden.
A new 3.2 mm H-F-X magic angle spinning dynamic nuclear polarization NMR (MAS DNP-NMR) probe was developed with a unique coil design with separate radiofrequency channels for H excitation and C or F detection to enable acquisition of H-F cross-polarization (CP) MAS experiments, direct-detected F spectra with proton decoupling, and acquisition on C with simultaneous double decoupling on the H and 19F channels as well as H-F-C double-CP experiments under low temperature MAS DNP conditions. We use these sequences to study AZD2811, which is an active pharmaceutical ingredient (API), in its pure dry state as well as in its corresponding drug delivery formulation consisting of drug-loaded polymeric nanoparticles (PNPs).
View Article and Find Full Text PDFBiomaterials
January 2025
Department of Laboratory Medicine and Department of Ultrasound, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 32, West Second Section, First Ring Road, Chengdu, 610072, Sichuan, China. Electronic address:
Incomplete radiofrequency ablation (iRFA) not only leaves residual tumor, but also render the residual tumor highly self-adaptable and immunosuppressive, consequently expediting residual tumor progression including relapse. To address it, radiofrequency dynamic therapy (RFDT) with identical trigger (namely radiofrequency) has been established and enabled by polyethylene glycol (PEG)-modified Fe-based single atom nanozyme (P@Fe SAZ). P@Fe SAZ can respond to radiofrequency field to produce reactive oxygen species (ROS), attaining the nanomedicine-unlocked low-temperature RFDT.
View Article and Find Full Text PDFJ Biomed Phys Eng
December 2024
Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: T thermometry is considered a straight method for the safety monitoring of patients with deep brain stimulation (DBS) electrodes against radiofrequency-induced heating during Magnetic Resonance Imaging (MRI), requiring different sequences and methods.
Objective: This study aimed to compare two T thermometry methods and two low specific absorption rate (SAR) imaging sequences in terms of the output image quality.
Material And Methods: In this experimental study, a gel phantom was prepared, resembling the brain tissue properties with a copper wire inside.
Angew Chem Int Ed Engl
December 2024
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, P. R. China.
Green ammonia synthesis using fluctuating renewable energy supply in decentralized process is a goal that has been long sought after. Ammonia synthesis with non-thermal plasma under mild conditions is a promising technology, but it faces the critical challenge of low energy efficiency. Herein, we develop an easily-scalable AuCu/Cu catalyst, which consists of a decimeter-scale metallic Cu antenna and nano-scale AuCu catalytic sites on metallic Cu surface, significantly enhancing the energy efficiency and ammonia yield in a radio-frequency (RF) plasma system.
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