Appropriate management of the patient with colorectal carcinoma depends on obtaining key prognostic and predictive information from the resection specimen. These include the quality of surgery, extent of lymph nodal clearance, presence of nodal disease, vascular invasion, residual disease post neoadjuvant treatment, and completeness of resection. A meticulous and structured approach to dissection of the resection specimen and subsequent histological examination by the pathologist is crucial in providing this information to the treating clinician. A good macroscopic examination also serves to audit the quality of other services including radiology, surgery, and oncology. This article attempts to review dissection and reporting guidelines with an evidence-based approach and hopes to guide pathologists to understand the basis behind the recommended protocols.
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http://dx.doi.org/10.4103/ijc.IJC_546_20 | DOI Listing |
Aesthetic Plast Surg
January 2025
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
Background: Prominent ears are a prevalent aesthetic concern, with numerous surgical techniques utilized in otoplasty procedures, without a widely approved gold standard. Traditional methods often leave residual deformities, reducing patient satisfaction.
Methods: We conducted a retrospective case series analysis involving 38 patients (30 Female, 8 Male) who underwent otoplasty to correct prominent ears for aesthetic purposes from January 2019 to December 2022.
Aesthetic Plast Surg
January 2025
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Background: Hollowness in the anteromedial, buccal, and lateral cheek regions is a common concern in aesthetic medicine, often resulting from age-related volume loss and structural changes. Advanced filler injection techniques that incorporate a thorough understanding of facial anatomy are critical for achieving optimal and safe outcomes.
Objective: To review and detail anatomically guided filler injection techniques for addressing hollowness in specific cheek regions, considering facial anatomy, ethnic variations, and patient-specific aesthetic goals.
Aesthetic Plast Surg
January 2025
Department of Body Contouring and Fat grafting Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33 Badachu Road, Shijingshan District, 100144, Beijing, People's Republic of China.
Background: Superficial autologous fat grafting is widely used for facial rejuvenation and regenerative treatments, yet its retention rate remains unpredictable. Enhancing the concentration of adipose-derived stem cells (ASCs) has been shown to improve graft retention. Mechanical fat processing techniques can reduce fat granules size for superficial injection as well as elevate the concentration of ASCs.
View Article and Find Full Text PDFHealth Res Policy Syst
January 2025
School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Background: The use of eHealth innovations is becoming increasingly important in improving health outcomes, especially for maternal and newborn health. However, planning and executing these innovations can be challenging due to their complex nature. To provide guidance and clarity on implementation approaches, researchers need to use implementation research (IR) tools.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
January 2025
Dartmouth Hitchcock Medical Center, Section of Allergy and Clinical Immunology, Lebanon, NH; Geisel School of Medicine at Dartmouth, Departments of Medicine and Pediatrics. Electronic address:
The art of clinical negotiation is an important, yet underappreciated aspect of medicine. Key components of negotiation include the need to consider principles over personalities, to explore all options before deciding on the best course, to realize if consensus cannot be achieved then compromise may still be possible, to work from evidence to incorporate contextual factors, and to stay evidence based. These principles can be helpful in many settings, including contract negotiation, drug pricing, and research.
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