Background: There is a trend in healthcare for developing models for predictions of disease to enable early intervention and improve outcome.
Instrument: We present the use of artificial intelligence algorithms that were developed by Gynisus Ltd. using mathematical algorithms.
Experience: Data were retrospectively collected on pregnant women that delivered at a single institution. Hundreds of parameters were collected and found to have different importance and correlation with the likelihood to develop gestational diabetes mellitus (GDM). We highlight 3 of 29 specific parameters that were important in pregestation and in early pregnancy, which have not been previously correlated with GDM.
Conclusion: This predictive tool identified parameters that are not currently being used as predictors in GDM, even before pregnancy. This tool opens the possibility of intervening on patients identified at risk for GDM and its complications. Future prospective studies are needed.
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http://dx.doi.org/10.1177/1932296820948883 | DOI Listing |
Heliyon
January 2025
Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh.
Background And Aims: Resistin is inflammatory adipocytokine released from adipose and other tissue. It is thought that it is related to insulin resistance and pathogenesis of gestational diabetes mellitus (GDM). This study was aimed to determine the level of serum resistin in mothers with GDM and normal glucose tolerance (NGT) in all trimesters to see whether it differs among different trimesters as well as between GDM and NGT.
View Article and Find Full Text PDFKidney Int Rep
January 2025
Department of General Practice, Institute of Clinical Medicine, University of Turku and Turku University Hospital, Turku, Finland.
Introduction: Smoking during pregnancy (SDP) seems to paradoxically decrease the likelihood of preeclampsia. We aimed to investigate the association between smoking and isolated proteinuria during pregnancy. In addition, we investigated the associations and potential interaction between smoking and proteinuria on the risk for preterm birth.
View Article and Find Full Text PDFDiabetes Metab Res Rev
January 2025
Division of Research, Kaiser Permanente Northern California, Pleasanton, California, USA.
Aims: Gestational diabetes mellitus (GDM) poses a significant risk for developing type 2 diabetes mellitus (T2D) and exhibits heterogeneity. However, understanding the link between different types of post-GDM individuals without diabetes and their progression to T2D is crucial to advance personalised medicine approaches.
Materials And Methods: We employed a discovery-based unsupervised machine learning clustering method to generate clustering models for analysing metabolomics, clinical, and biochemical datasets.
Eur J Pediatr
January 2025
School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Unlabelled: While previous research has established correlations between pre-pregnancy body mass index (BMI), late-pregnancy blood glucose, and late-pregnancy blood lipid levels during pregnancy and offspring's physical development, the underlying mechanism of their interaction remains elusive. A birth cohort study was conducted on pregnant women, who are biologically female, delivering at a tertiary hospital in Wuhan City between May 2023 and April 2024, encompassing 1620 participants. We collected maternal socio-demographic data through questionnaires and obtained information on fasting blood glucose (FPG), lipid levels during the third trimester, and neonatal physical development from medical records.
View Article and Find Full Text PDFSci Rep
January 2025
Hainan Women and Children's Medical Center, Haikou, 571199, Hainan, China.
This observational investigation aimed to explore potential risk factors for anemia in pregnancy. Firstly, a cross-sectional study was conducted, encompassing a review of clinical data of 43,201 pregnant women admitted to the Hainan Women and Children's Medical Center between January 2017 and December 2020. Comparison between women with and without anemia in pregnancy revealed significant differences between the two groups concerning age, gestational diabetes, hypothyroidism, hyperthyroidism, chronic hepatitis B virus infection, syphilis infection, and human immunodeficiency virus infection.
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