Second to fourth digit ratio (2D:4D) is associated with dementia in women.

Early Hum Dev

Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. Electronic address:

Published: October 2020

Alzheimer's disease is characterized by sex differences that may involve sex hormone exposure during development. Finger length ratios, an indirect measure of prenatal androgen exposure, were found to significantly differ in women with and without dementia. This finding links a relatively feminine in utero development with vulnerability to dementia in women.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484057PMC
http://dx.doi.org/10.1016/j.earlhumdev.2020.105152DOI Listing

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