Background: Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in people older than 50 years.
Case Description: A 66-year-old man with hypertension consulted the ophthalmologist because of increasing visual-field loss in his right eye; 3 weeks previously he had noticed visual decline in the same eye when he woke up. The eye was not painful. Further questioning revealed that the patient also suffered from sleep apnoea. Following additional investigations we diagnosed NAION.
Conclusion: There is no effective treatment for NAION. Risk factors such as high blood pressure and obstructive sleep apnoea syndrome can be addressed to reduce the risk of reoccurrence of NAION in the other eye.
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Front Neurosci
December 2024
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Introduction: Traditional extraocular electrical stimulation typically produces diffuse electric fields across the retina, limiting the precision of targeted therapy. Temporally interfering (TI) electrical stimulation, an emerging approach, can generate convergent electric fields, providing advantages for targeted treatment of various eye conditions.
Objective: Understanding how detailed structures of the retina, especially the optic nerve, affects electric fields can enhance the application of TI approach in retinal neurodegenerative and vascular diseases, an essential aspect that has been frequently neglected in previous researches.
Ophthalmic Genet
January 2025
Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.
Introduction: Phosphoribosyl pyrophosphate synthetase 1 () is an X-linked gene critical for nucleotide metabolism. Pathogenic variants cause three overlapping phenotypes: Arts syndrome (severe neurological disease), Charcot-Marie-Tooth type 5 [CMTX5] (peripheral neuropathy), and non-syndromic sensorineural hearing loss (SNHL). Each may be associated with retinal dystrophy.
View Article and Find Full Text PDFJ Am Anim Hosp Assoc
January 2025
Laboratory of Veterinary Clinical Oncology, Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan (T.M.).
Although intracranial and spinal cord meningioma prognoses have been reported, few studies have evaluated the outcomes and prognoses of orbital and optic nerve meningiomas in dogs. We aimed to evaluate the outcomes of canine orbital meningiomas. The seven dogs included were cytologically or histopathologically diagnosed with meningiomas.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: This study aimed to comprehensively explore the thickness and topographic distributions of retinal vessel alterations of different myopic eyes by using swept-source OCT angiography (SS-OCTA).
Methods: One hundred myopes were included in this observational cross-sectional study. All participants underwent a series of ocular examinations of biometrical parameters, including spherical equivalent refraction (SER), axial length (AL), intraocular pressure (IOP), curvature radius (CR), and others.
Cureus
December 2024
Neuro Ophthalmology, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Puducherry, IND.
A five-year-old female came with a history of frequent rubbing of the right eye and noticed prolonged elevation of her head since birth, informed by her mother. On ocular examination, the best corrected visual acuity shown in the right eye was 1/60, and the left eye was 6/6, with proptosis in both eyes. Fundus examination showed both eyes having pale discs.
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