Goal-directed actions transiently depend on dorsal hippocampus.

Nat Neurosci

Decision Neuroscience Laboratory, School of Psychology, University of New South Wales, Sydney, New South Wales, Australia.

Published: October 2020

The role of the hippocampus in goal-directed action is currently unclear; studies investigating this issue have produced contradictory results. Here we reconcile these contradictions by demonstrating that, in rats, goal-directed action relies on the dorsal hippocampus, but only transiently, immediately after initial acquisition. Furthermore, we found that goal-directed action also depends transiently on physical context, suggesting a psychological basis for the hippocampal regulation of goal-directed action control.

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http://dx.doi.org/10.1038/s41593-020-0693-8DOI Listing

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