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Photothermal therapy technology of metastatic colorectal cancer. | LitMetric

Photothermal therapy technology of metastatic colorectal cancer.

Am J Transl Res

Department of Colorectal Surgery, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-Sen University Guangzhou 510655, Guangdong, China.

Published: July 2020

AI Article Synopsis

  • * Photothermal therapy (PTT) is an emerging method with potential for treating mCRC, and the review discusses various traditional and innovative approaches like surgery, chemotherapy, and PTT.
  • * The review also covers the use of different nanomaterials in PTT for CRC, examines combined applications with other methods, and suggests future research directions for improving treatment outcomes.

Article Abstract

Colorectal cancer (CRC) is one of the most common malignancies. The current treatments of metastatic colorectal cancer (mCRC) are ineffective and the bottleneck problem. It is of significance to explore effective new therapeutic strategies to eradicate mCRC. Photothermal therapy (PTT) is an emerging technology for tumor therapy, with the potential in the treatment of mCRC. In this review, the current treatment approaches to mCRC including surgery, radiotherapy, chemotherapy interventional therapy, biotherapy, and photothermal therapy are reviewed. In addition, we will focus on the various kinds of nanomaterials used in PTT for the treatment of CRC both in vitro and in vivo models. In conclusion, we will summarize the combined application of PTT with other theranostic methods, and propose future research directions of PTT in the treatment of CRC.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407689PMC

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