Particulate matter (PM) has demonstrably increased rates of cardiovascular and respiratory related disease; thus, a low-cost sensor that accurately measures PM is desirable including for smaller and more private environments such as residential homes. The low-cost Dylos and the Utah Modified Dylos Sensor (UMDS) have been shown to be highly correlated with references instruments for measuring particle counts and aerosol concentrations, which makes them useful tools for air quality studies. An analytical calibration equation (calibration) is used to describe the linear relationship between the UMDS and a reference instrument, providing the best estimate of PM concentrations when the UMDS is operated. In this study, an investigation of measurement variation of a UMDS was performed using a low-cost calibration technique to determine differences between the brand new UMDS pre-calibration equation (Pre), a contaminated UMDS post-calibration equation (Post), and a cleaned UMDS clean calibration equation (CC). The UMDS were calibrated against a high-grade aerosol spectrometer (Grimm model 1.109) as a reference instrument. Calibrations took place in a home or office environment. Counts per volume units from the UMDS were matched to the Grimm's for comparison. The investigation of the UMDS for measurement variation was performed for the approximate estimates of PM by using the small bin (i.e. ≥0.50μm) subtracted from the large bin (i.e. ≥2.5μm), and for total particulates by using the large bin. Linear regressions were performed between the UMDS and the Grimm per calibration event, which produced R values and slopes that were indicative of measurement variation. Data exceeding the upper limit of quantification (ULOQ) of 106,000 particles/liter and the lower limit of quantification (LLOQ) of 4 particles/liter were excluded from statistical comparison. R values greater or equal to 0.70 were used to assess measurement variation as a quality control standard for valid comparisons. A rank sum statistical test between calibration comparisons was performed. Pre/Post and Pre/CC had significant differences indicating measurement variation. Post/CC did not have any significant differences; cleaning the UMDS had no effect and did not demonstrate measurement variation. Reasons for measurement variation may include instrument contamination (dust/dirt), hardware degradation, altered fan flow rates, and potentially inadequate cleaning of the UMDS. Future work may investigate the rate of measurement variation in order to develop a recommended re-calibration schedule in order to maintain the most accurate estimates of PM for UMDS in long-term operation.
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http://dx.doi.org/10.1016/j.jaerosci.2019.04.017 | DOI Listing |
H*10 neutron dosimetry (unlike gamma dosimetry), requires consideration of neutron energy spectra due to the 20× variation of the weight factor over the thermal-to-fast energy range, as well as the neutron radiation field dose rates ranging from cosmic, ~.01 μSv h-1 levels to commonly encountered ~10-200 μSv h-1 in nuclear laboratories/processing plants, and upwards of 104 Sv h-1 in nuclear reactor environments. This paper discusses the outcome of the comparison of spectrum-weighted neutron dosimetry covering thermal-to-fast energy using the novel H*-TMFD spectroscopy-enabled sensor system in comparison with measurements using state-of-the-art neutron dosimetry systems at SRNS-Rotating Spectrometer (ROSPEC), and non-spectroscopic Eberline ASP2E ("Eberline") and Ludlum 42-49B ("Ludlum") survey instrumentation.
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January 2025
Author Affiliations: School of Nursing, Center for Research Development and Scholarship, Vanderbilt University (Ms Sommer, Dr Muchira, Ms Chinni, and Dr Mogos); Department of Obstetrics and Gynecology, Vanderbilt University Medical Center (Dr Garrison); Annette and Irwin Eskind Family Biomedical Library, Vanderbilt University, Nashville, Tennessee (Ms Walden); and Medical College of Georgia, Augusta University, Augusta, Georgia (Mr van der Eerden).
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View Article and Find Full Text PDFPLoS One
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Department of Otolaryngology, University Hospital Regensburg, Regensburg, Germany.
The inferior colliculus is a key nucleus in the central auditory pathway, integrating acoustic stimuli from both cochleae and playing a crucial role in sound localization. It undergoes functional and structural development in childhood and experiences age-related degeneration later in life, contributing to the progression of age-related hearing loss. This study aims at finding out, whether the volume of the human inferior colliculus can be determined by analysis of routinely performed MRIs and whether there is any age-related variation.
View Article and Find Full Text PDFAnnu Rev Entomol
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Laboratory of Genetics, Wageningen University & Research, Wageningen, The Netherlands.
Major changes in genetic variation are generally considered deleterious to populations. The massive biodiversity of insects distinguishes them from other animal groups. Insect deviant effective population sizes, alternative modes of reproduction, advantageous inbreeding, endosymbionts, and other factors translate to highly specific inbreeding and outbreeding outcomes.
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