Objective: Ample research documented the effects of guiding principles in people's lives, as reflected in personal values, on a variety of behaviors. But do these principles universally guide behaviors across all cultural contexts? To address this question, we investigated the effect of cross-cultural differences in the strength of social norms (i.e., tightness-looseness) on value-behavior relationships.
Method: Using the archival data from the World Value Survey for 24 nations (N = 38,924; 51.40% female; M = 44.98, SD = 16.87), a multi-level analysis revealed that cultural tightness moderated the effects of individual differences in personal values on behaviors from different life-domains.
Results: As hypothesized, the relationships between self-transcendence values with civic involvement and pro-environmental behaviors, and between conservation values with religious behavior were significantly stronger in loose cultures that have weak norms and were almost nonexistent in tight cultures that have strong norms, even when controlling for individualism-collectivism or GDP.
Conclusions: Thus, despite the common belief that people behave in line with their guiding principles, our findings suggest this might not be the case in cultural contexts that put a strong emphasis on norms.
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Adv Biotechnol (Singap)
October 2024
State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Agriculture and Biotechnology, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, China.
The principle of the "growth-defense trade-off" governs how plants adjust their growth and defensive strategies in response to external factors, impacting interactions among plants, herbivorous insects, and their natural enemies. Mineral nutrients are crucial in modulating plant growth and development through their bottom-up effects. Emerging evidence has revealed complex regulatory networks that link mineral nutrients to plant defense responses, influencing the delicate balance between growth and defense against herbivores.
View Article and Find Full Text PDFHeliyon
January 2025
School of Digital Science, Universiti Brunei Darussalam, Gadong BE1410, Brunei Darussalam.
Microlearning has become increasingly popular not only in education sector but also in corporate sector in recent years. However, its definition and didactics conceptualization, integration into instruction design, and effects on learning outcomes remain largely underexplored in terms of synthesized findings. Consequently, challenges persist in clarifying microlearning definition, and didactics, and designing effective microlearning instruction to yield improved learning outcomes.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Foxp3-expressing CD4 regulatory T (Treg) cells play a crucial role in suppressing autoimmunity, tolerating food antigens and commensal microbiota, and maintaining tissue integrity. These multifaceted functions are guided by environmental cues through interconnected signaling pathways. Traditionally, Treg fate and function were believed to be statically determined by the forkhead box protein Foxp3 that directly binds to DNA.
View Article and Find Full Text PDFContemp Clin Trials Commun
April 2025
University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ, USA.
Background: Cancer survivor-caregiver dyads from underrepresented racial and ethnic groups and those with lower socioeconomic status are less likely to participate in clinical research. Sociocultural and socioeconomic barriers perpetuate health inequity and increase disparities in cancer care.
Purpose: We describe our systematic approach to recruiting and retaining diverse survivor-caregiver dyads in supportive cancer care studies.
Toxicol Pathol
January 2025
Eli Lilly and Company, Indianapolis, Indiana, USA.
Nonhuman primates (NHPs) have been and remain a highly valuable animal model with an essential role in translational research and pharmaceutical drug development. Based on current regulatory guidelines, the nonclinical safety of novel therapeutics should be evaluated in relevant nonclinical species, which commonly includes NHPs for biotherapeutics. Given the practical and ethical limitations on availability and/or use of NHPs and in line with the widely accepted guiding "3Rs" (replace, reduce, and refine) principles, many approaches have been considered to optimize toxicity study designs to meaningfully reduce the number of NHPs used.
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