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Environmental pollutant exposure can exacerbate COVID-19 neurologic symptoms. | LitMetric

Environmental pollutant exposure can exacerbate COVID-19 neurologic symptoms.

Med Hypotheses

Biological Models Laboratory, Department of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila, Ermita, Manila 1000, Philippines. Electronic address:

Published: November 2020

AI Article Synopsis

Article Abstract

Neurologic symptoms have been reported in some COVID-19 patients. However, little is known on what factors influence the risk of developing these symptoms. While some studies suggest that exposure to pollution is associated with higher rates of SARS-CoV-2 infection, its role is unknown in the development of neurologic symptoms in COVID-19 patients. The response of the central nervous system (CNS) to a SARS-CoV-2 infection may be influenced by its inflammatory state. Interestingly, environmental pollutants such as particulate matter may have neuroinflammatory effects, providing a possible link between exposure to these pollutants and the outcome of SARS-CoV-2 infection in the CNS. This article explores the hypothesis that the neurologic symptoms in COVID-19 may be exacerbated through a neuroinflammatory mechanism that is promoted by environmental pollutant exposure.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382920PMC
http://dx.doi.org/10.1016/j.mehy.2020.110136DOI Listing

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