Weight loss during medical weight management does not predict weight loss after bariatric surgery: a retrospective cohort study.

Surg Obes Relat Dis

Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom; Department of Diabetes and Endocrinology, University Hospital Birmingham Foundation Trust, Birmingham, United Kingdom; Centre for Endocrinology Diabetes and Metabolism (CEDAM), Birmingham Health Partners, Birmingham, United Kingdom.

Published: November 2020

Background: Many bariatric surgical centers mandate achieving weight loss targets through medical weight management (MWM) programs before offering bariatric surgery, but the evidence for this is unclear.

Objectives: To examine the relationship between weight changes during (1) MWM, and (2) preoperative low-energy-diet (LED), and weight changes at 12 and 24 months after surgery.

Setting: Multicenter community- and acute-based MWM services referring to one regional bariatric center, United Kingdom.

Methods: A retrospective cohort study of patients who attended MWM and then underwent a primary laparoscopic bariatric procedure (adjustable gastric banding [LAGB], or Roux-en-Y gastric bypass [RYGB]) in a single bariatric center in the United Kingdom between 2013 and 2015. Data were collected from patient electronic records.

Results: Two hundred eight patients were included (LAGB n = 128, RYGB n = 80). Anthropometric data were available for 94.7% and 88.0% of participants at 12 and 24 months, respectively. There was no relationship between weight loss during MWM and after surgery at either 12 or 24 months. Weight loss during the preoperative LED predicted greater weight loss after LAGB (β = .251, P = .006) and less weight loss after RYGB (β = -.390, P = .003) at 24 months, after adjusting for age, sex, ethnicity, baseline weight, and LED duration.

Conclusions: Weight loss in MWM does not predict greater weight loss outcomes up to 24 months after LAGB or RYGB. Greater weight loss during the preoperative LED predicted greater weight loss after LAGB and less weight loss after RYGB. Our results suggest that patients should not be denied bariatric surgery because of not achieving weight loss in MWM. Weight loss responses to preoperative LEDs as a predictor of postsurgical weight loss requires further investigation.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.soard.2020.06.049DOI Listing

Publication Analysis

Top Keywords

weight loss
60
weight
20
greater weight
16
loss
14
bariatric surgery
12
loss mwm
12
medical weight
8
weight management
8
retrospective cohort
8
cohort study
8

Similar Publications

Fetal growth restriction (FGR) is a common complication of pregnancy, which seriously endangers fetal health and still lacks effective therapeutic targets. Clostridium difficile (C. difficile) is associated with fetal birth weight, and its membrane vesicles (MVs) are pathogenic vectors.

View Article and Find Full Text PDF

Background/aim: A standard mouse model of pulmonary fibrosis has been created by intratracheal or intraperitoneal administration of bleomycin. However, a difficulty presented by this traditional method is its high mortality rate of more than 50% after bleomycin administration. In this study, we aimed to establish a unilateral lung disease model and to assess its feasibility and usefulness.

View Article and Find Full Text PDF

Background/aim: Body weight loss (BWL) after gastrectomy for gastric cancer (GC) decreases postoperative quality of life and survival in patients with GC. This study aimed to evaluate the effect of oral nutritional supplements composed of high protein on BWL in the early period following gastrectomy.

Patients And Methods: Pre- and postoperative body weight and skeletal muscle mass were measured using bioelectrical impedance analysis in patients undergoing radical gastrectomy for GC and analyzed retrospectively.

View Article and Find Full Text PDF

Background/aim: Cancer cachexia is characterized by weight loss with a specific decrease in skeletal muscle and adipose tissue. In Japan, anamorelin, which has a novel mechanism of action, was approved in 2021 for the treatment of cancer cachexia. However, little information is available on its safety in routine clinical care, in particular the occurrence of conduction defects as adverse reactions.

View Article and Find Full Text PDF

Background/aim: The present study aimed to assess the relationship between the maximum standardized uptake value (SUVmax) on F-fluorodeoxyglucose positron emission tomography computed tomography (F-FDG-PET/CT) and the geriatric nutritional risk index (GNRI) in patients with soft-tissue sarcomas (STSs).

Patients And Methods: The present single-center retrospective observational study included patients who underwent F-FDG-PET/CT and for whom serum albumin levels, height, and body weight were measured prior to therapeutic intervention.

Results: A total of 81 patients were included in the study.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!