Pierre Robin sequence (PRS) is characterized by the triad of retrognathia, glossoptosis, and airway obstruction. PRS may occur in isolation or in conjunction with other syndromes. Distinguishing isolated and syndromic forms of PRS helps clinicians decide the management plan. We describe two cases of PRS of Indian ethnicity and describe some of the difficulties that we faced while distinguishing isolated PRS from syndromic PRS. Both cases had a similar clinical presentation. However, one of the cases had a positive family history of congenital deafness and cleft palate, whereas the other case had apparent upper limb anomalies. These facts heightened the suspicion of an associated syndrome. However, based on the available facts and after thorough investigations, a tentative diagnosis of isolated PRS was made for both the patients. Both the cases were managed conservatively and were advised a long-term follow-up. When the associated anomalies are few, minor or concealed at birth, longitudinal follow-up of all PRS cases combined with thorough diagnostics including chromosomal analysis could help differentiate syndromic PRS from isolated PRS. Regardless, all cases of PRS require a multidisciplinary approach.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.14712/18059694.2020.23 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Guardians of resistance and virulence: detection of mec, femA, Van, pvl, hlg and spa genes in methicillin and vancomycin-resistant Staphylococcus aureus from clinical and food samples in Southwestern Nigeria.
BMC Microbiol
November 2024
Multidisciplinary Research Laboratory, Osun State University, Osogbo, 230212, Nigeria.
Background: Staphylococcus aureus strains are highly virulent and associated with an eclectic range of severe nosocomial and community-acquired infections.
Objectives: This study assessed methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA/VRSA) from clinical and ready-to-eat (RTE) food sources, screened for antibiotic resistance; and molecular determinants of antibiotic and virulence genes.
Methods: Altogether, 465 clinical and RTE food samples were analyzed via conventional microbiological techniques and S.
Enzymatically extracted ulvans restrict viruses via STING signaling and type I interferon after cellular entry.
Carbohydr Polym
January 2025
Key Laboratory of Tropical Biological Resources of Ministry of Education and One Health Institute, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China. Electronic address:
Ulvans, abundant natural polysaccharides produced by Ulvales, have been recognized for antiviral activities, though the underlying mechanisms are not fully understood. In this study, we focused on two polysaccharides and one oligosaccharide, which were extracted enzymatically from Ulva prolifera and named as PR1 (13.5 kDa), PR2 (7.
View Article and Find Full Text PDFAssociations between self-compassion and moral injury among healthcare workers: A cross-sectional study.
Nurs Ethics
November 2024
School of Psychology, Laval University, Quebec, Canada.
Background: Healthcare workers (HCWs) can face situations that conflict with their moral beliefs, leading to moral injury, an adverse psychological consequence that was more frequent during the COVID-19 pandemic. Self-compassion is a potential coping mechanism for moral injury by encouraging acceptance of human limitations and suffering.
Objectives: This study aimed to examine the associations between self-compassion components and moral injury prevalence among HCWs in Quebec, Canada, during the COVID-19 pandemic.
Epidemiology of Coloboma: Prevalence and Patterns in Texas, 1999-2014.
Birth Defects Res
November 2024
Section of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Article Synopsis
- - Coloboma is a rare congenital condition where part of the eye's tissue is missing, potentially leading to visual impairments; this study analyzed data from the Texas Birth Defects Registry spanning 1999 to 2014 to better understand its prevalence.
- - The research identified 1,587 coloboma cases, noting that about 58.8% were nonsyndromic, and highlighted key factors affecting prevalence, such as maternal education, race/ethnicity, plurality of births, and maternal diabetes.
- - The findings suggest a rising trend in coloboma cases over the years and could help target screening efforts for at-risk populations, potentially improving outcomes for future children.
Effect of pneumococcal conjugate vaccination on pneumococcal carriage in hospitalised children aged 2-59 months in Mongolia: an active pneumonia surveillance programme.
Lancet Microbe
December 2024
Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of Microbiology and Immunology, University of Melbourne-Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Background: Data on changes in pneumococcal serotypes in hospitalised children following the introduction of the pneumococcal conjugate vaccine (PCV) in low-income and middle-income countries are scarce. In 2016, Mongolia introduced the 13-valent PCV (PCV13) into the national immunisation programme. We aimed to describe the trend and impact of PCV13 introduction on pneumococcal carriage in hospitalised children aged 2-59 months with pneumonia in Mongolia over a 6-year period.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!