Foot-and-mouth disease virus (FMDV) serotype Asia1 is prevalent in India and is responsible for a minor proportion of FMD outbreaks. Globally, serotype Asia1 is grouped into nine different groups (GI-IX) based on genetic analysis. In India, only Asia1/G-III and Asia1/G-VIII have been documented so far. Phylogenetic analysis of recent serotype Asia1 isolates from India revealed the emergence of Asia1/G-IX. The Asia1/G-IX lineage shares recent common ancestry with Asia1/G-VIII dating to 2016. The root state posterior probabilities of Asia1/G-VIII are inclusive and there may have been either an incursion of the virus from Bangladesh, where it was first identified, or in situ evolution of the virus within India, which is an intriguing possibility.
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http://dx.doi.org/10.1007/s00705-020-04766-5 | DOI Listing |
Vaccine
January 2025
Indian Council of Agricultural Research (ICAR)-Indian Veterinary Research Institute (IVRI), Hebbal, Bengaluru 560024, India. Electronic address:
As pregnancy can adversely affect the immune response of vaccination against foot and mouth disease virus (FMDV) due to physiological immunosuppressive milieu, we tested the effect of FMDV vaccination during mid-gestation on the antibody response. Pregnant and non-pregnant cows of crossbred and indigenous breed (n = 28/group) were vaccinated with inactivated FMD vaccine covering O, A, and Asia1 serotypes and the sera were harvested at weekly interval till day 42 post-vaccination. Virus neutralization test (VNT) was done and the analysis of log VN antibody titer by mixed model ANOVA indicated that pregnancy did not significantly affect the log VN titer for FMDV serotype O and Asia1.
View Article and Find Full Text PDFVirus Res
January 2025
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh. Electronic address:
Foot-and-mouth disease (FMD) is a highly contagious transboundary disease prevalent across the Asian continent, affecting both wild and domestic artiodactyls. The disease is caused by a virus belonging to the Aphthovirus genus of the Picornaviridae family which is categorized into seven serotypes: C, O, A, SAT1, SAT2, SAT3, and Asia1. The virus spreads through direct and indirect contact, including semen, meat, fomites, ingestion, and aerosols.
View Article and Find Full Text PDFSci Rep
October 2024
Department of Microbiology, University of Dhaka, Dhaka, 1000, Bangladesh.
PLoS Pathog
October 2024
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, P. R. China.
Virus Genes
October 2024
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
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