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[Invasive candidiasis: A view to central nervous system infection]. | LitMetric

[Invasive candidiasis: A view to central nervous system infection].

Rev Argent Microbiol

Laboratorio de Inmunidad Innata a Patógenos Fúngicos, Departamento de Bioquímica Clínica, Córdoba, Argentina; Centro de Investigaciones en Bioquímica Clínica e Inmunología, CIBICI-CONICET, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina; Servicio de Infectología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina; Research Group of Immunology and Mycology, Córdoba, Argentina. Electronic address:

Published: October 2021

AI Article Synopsis

Article Abstract

Candidemia is the most frequent invasive mycosis in hospitalized patients worldwide. Fungal infection in central nervous system is a life-threatening complication which aggravates patients' prognosis. This article summarizes relevant aspects on the clinical characteristics of this pathology, mechanisms of fungus invasion, local immune response to Candida albicans and the impact of genetic defects on innate immune receptors that increase susceptibility to the acquisition of this form of mycosis.

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Source
http://dx.doi.org/10.1016/j.ram.2020.06.003DOI Listing

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