Our patient presented with a mild upper respiratory infection, which quickly developed into atypical pneumonia. Although atypical pneumonia is a common clinical presentation, our case is unique due to the rare hematologic complications associated with the underlying etiology of this atypical pneumonia case. Most cases of atypical pneumonia are simple, but ours developed immune thrombocytopenic purpura (ITP), which is a rare complication associated with an acute Mycoplasmapneumoniae infection (evidenced by positive IgM titers). Although our patient did not develop significant bleeding, our review of the literature demonstrated that ITP associated with M. pneumoniae infection can be fatal. Platelet count should be closely monitored and promptly treated.
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http://dx.doi.org/10.7759/cureus.8955 | DOI Listing |
Infect Drug Resist
January 2025
Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People's Republic of China.
Background: Rapid and accurate identification of causative organisms and prompt initiation of pathogen-targeted antibiotics are crucial for managing atypical pneumonia. The widespread application of targeted next-generation sequencing (t-NGS) in clinical practice demonstrates significant targeted advantages in rapid and accurate aetiological identification and antimicrobial resistance genes detection, particularly for difficult-to-culture, rare, or unexpected pathogens. An alarming surge of acquired macrolide resistance (MR) in (MP) presents a substantial challenge for the clinical selection of pathogen-targeted antibiotics worldwide, especially for fluoroquinolone-restricted pediatric patients with limited options available.
View Article and Find Full Text PDFIJID Reg
March 2025
University of Insubria, Department of Medicine and Technology Innovation Varese, Varese, Italy.
We report an increase of () respiratory infections during 2023-2024. The positive rate in 2024 is higher at 68 per 1668 (5%) compared with 2023 at nine per 1264 (0.7%), highlighting the increased circulation in north-west Italy.
View Article and Find Full Text PDFAME Case Rep
October 2024
Division of Respiratory and Critical Care Medicine, Jiangyin People's Hospital Affiliated to Nantong, Jiangyin, China.
Background: There are hundreds of pathogens that cause lung infections. Compared to infections caused by a single pathogen, mixed infections account for a larger proportion of pulmonary infections and have a more severe clinical presentation, while treatment options differ between the two. We aimed to explore the advantages of metagenomic next-generation sequencing (mNGS) in the diagnosis and treatment of mixed infections.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Psychology, University of Surrey, Guildford, United Kingdom.
Background: Atypical interoception has been observed across multiple mental health conditions, including anxiety disorders and depression. Evidence suggests that not only pathological anxiety, but also heightened levels of state anxiety and stress are associated with interoceptive functioning. This study aimed to investigate the effects of the recent Coronavirus SARS-CoV-2 pandemic on self-reported interoception and mental health, and their relationship.
View Article and Find Full Text PDFRespir Med Case Rep
December 2024
Central RI [Research Institute] of Epidemiology, Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor), Moscow, Russia.
According to WHO, dengue fever (DF) is currently endemic to more than 100 countries in various regions of Africa, America, and Asia; outbreaks have been reported in Europe. In the Russian Federation, there is a much smaller proportion of children among those infected due to the imported nature of the infection. We described a clinical case of imported dengue fever in an adolescent girl in Moscow after a 5-day vacation.
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