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http://dx.doi.org/10.1212/WNL.0000000000010579 | DOI Listing |
J Breath Res
January 2025
School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Rd, Qingdao, Shandong, 266003, CHINA.
Lung cancer is one of the most common malignancy in the world, and early detection of lung cancer remains a challenge. The exhaled breath condensate (EBC) from lung and trachea can be collected totally noninvasively. In this study, our aim is to identify differential metabolites between non-small cell lung cancer (NSCLC) and control EBC samples and discriminate NSCLC group from control group by orthogonal projections to latent structures-discriminant analysis (OPLS-DA) models.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department of Laboratory Medicine, Guangdong Provincial Key Laboratory of Precision Medical Diagnostics, Guangdong Engineering and Technology Research Center for Rapid Diagnostic Biosensors, Guangdong Provincial Key Laboratory of Single Cell Technology and Application, School of Laboratory Medicine and Biotechnology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China.
Circular RNAs in extracellular vesicles (EV-circRNAs) are gaining recognition as potential biomarkers for the diagnosis of gastric cancer (GC). Most current research is focused on identifying new biomarkers and their functional significance in disease regulation. However, the practical application of EV-circRNAs in the early diagnosis of GC is yet to be thoroughly explored due to the low accuracy of EV-circRNAs analysis.
View Article and Find Full Text PDFJ Clin Exp Dent
December 2024
Faculty of Sciencies of Health. Universidad Nacional del Callao.
Background: To evaluate the performance of different prediction models based on machine learning to predict the presence of early childhood caries.
Material And Methods: Cross-sectional analytical study. The sociodemographic and clinical data used came from a sample of 186 children aged 3 to 6 years and their respective parents or guardians treated at a Hospital in Ica, Peru.
Cureus
December 2024
General Surgery, All India Institute of Medical Sciences, Guwahati, Guwahati, IND.
The perineurioma (PN) is a benign neoplasm with perineural origin. It can be of two types, i.e.
View Article and Find Full Text PDFAlzheimers Dement (Amst)
January 2025
Non Invasive Brain Stimulation Unit Istituto di Ricovero e Cura a Carattere Scientifico Santa Lucia Rome Italy.
Introduction: Blood-based biomarkers seem promising for the diagnosis of Alzheimer's disease (AD).
Methods: We performed a systematic review and meta-analysis on the potential of blood phosphorylated Tau181 (p-tau181) to differentiate amyloid-positive (A+) and amyloid-negative (A-) subjects. Two meta-analyses were conducted, showing the mean p-tau values in blood and cerebrospinal fluid (CSF) in the A+ and A- group, and the second comparing the mean p-tau concentrations in blood and CSF among A+ versus A- participants, by laboratory assessment method.
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