Q-switched laser is considered a gold standard treatment for Nevus of Ota (NO). We report how few laser sessions in long intervals of time may achieve satisfying outcomes reducing the rate of possible procedure-linked side effects such as burning, cornea injuries, or hyperpigmentation. NO represents a congenital dermal melanocytosis in the trigeminal distribution majorly occurring in Asian individuals. Multiple reports have shown efficacy and safety of Q-switched laser for the treatment of this condition, but they were based on an empiric regimen, often leading to unnecessary overtreatments. At the best of our knowledge, no long-term follow-up observations of single laser sessions have been conducted to assess the proper intervals and number of treatments. A 36-year-old Asian woman, Fitzpatrick skin type IV with clinical diagnosis of NO, was treated with 1064 nm 6 ns Q-switched laser one session per year for a total of two sessions. Clinical result was valued by two physicians independently using standardized and polarized light. No use of general anesthesia or sedation was needed in our experience. Corneal shields have been used. After only two sessions of the Q-switched laser performed 1 year apart, the result was excellent with a 95% of clinical response. No side effect was observed. In our experience, Q-switched Nd:YAG laser is an effective treatment for NO with no necessity of high number of treatments. A larger population is needed to confirm this preliminary result.
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http://dx.doi.org/10.1089/photob.2020.4812 | DOI Listing |
Lasers Med Sci
January 2025
Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
To investigate the efficacy and safety of picosecond (PS) and nanosecond (NS) 1064-nm neodymium-doped yttrium aluminum garnet (Nd: YAG) laser in treating Café-au-lait macules (CALMs). We retrospectively analyzed the medical records of patients with CALMs, who were treated with PS or NS 1064-nm lasers from January 2020 to January 2022. The efficacy was determined based on the before and after pictures by two independent investigators.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Cornell University, Ithaca, USA.
Purpose: Photobiomodulation (PBM) is a non-invasive therapeutic procedure that consists of irradiating a local area of the skin with red and near-infrared lasers or light emitting diodes (LEDs). Local PBM has been studied as a method to improve exercise performance and recovery. This review aims to evaluate the efficacy of whole-body PBM for exercise performance and recovery, comparing its findings to the established effects of localized PBM.
View Article and Find Full Text PDFRev Sci Instrum
January 2025
Institute for Physical Chemistry, University of Göttingen, 37077 Göttingen, Germany.
Surface science instruments require excellent vacuum to ensure surface cleanliness; they also require control of sample temperature, both to clean the surface of contaminants and to control reaction rates at the surface, for example, for molecular beam epitaxy and studies of heterogeneous catalysis. Standard approaches to sample heating within high vacuum chambers involve passing current through filaments of refractory metals, which then heat the sample by convective, radiative, or electron bombardment induced heat transfer. Such hot filament methods lead to outgassing of molecules from neighboring materials that are inadvertently heated; they also produce electrons and ions that may interfere with other aspects of the surface science experiment.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
Department of Ophthalmology, Peking University Third Hospital, No 49 Huayuan North Road, Haidian District, Beijing, 100191, China.
Purpose: To evaluate clinical outcomes and visual quality 12 months after small incision lenticule extraction (SMILE) for correction of myopia with or without astigmatism in patients during the incipient phase of presbyopia.
Setting: Peking University Third Hospital, Beijing, China.
Design: Retrospective observation study.
Phys Rev Lett
December 2024
Temple University, Department of Physics, Philadelphia, Pennsylvania 19122, USA.
We have produced state selective molecular angular momentum orientation using dressed states created by a cw optical field. The experiment was carried out with Li_{2} molecules and a combination of left- and right-hand circularly polarized lasers. Our approach exploits the dependence of the Rabi frequency on the quantum number M, which makes it possible to achieve complete M-state selectivity and thus molecular angular momentum orientation relative to laboratory frame space-fixed axes.
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