Series of thioether derivatives containing 4-methylumbelliferone fused oxazole moiety were designed and synthesised, their structures were fully characterized by H NMR, C NMR and HR-ESI-MS as well. Moreover, the antifungal potency of the title compounds were preliminarily evaluated for their possible use as a fungicide. Meanwhile, ethyl thioethers and displayed remarkable inhibitory effect against the mycelium growth of and with EC of 12-16 μg/mL. Furthermore, compounds and also exhibited > 88% protective and curative effect against on tomato fruits at 90 μg/mL. Additionally, the environmental toxicity of the title compounds against the brine shrimp were evaluated as well. The results indicated that most of the title compounds exhibited weak toxic to aquatic organism
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2020.1798665 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Revised Title - Quercetin Combined with Ciprofloxacin and Gentamicin Inhibits Biofilm Formation and Virulence in Staphylococcus aureus.
Microb Pathog
January 2025
Department of Molecular Biology & Bioinformatics, Tripura University (A Central University), Suryamaninagar-799022, Tripura, India. Electronic address:
Biofilm formation, extracellular substance synthesis, and virulence factor production all have a major impact on drug tolerance and infection propagation caused by Staphylococcus aureus. Flavonoid compounds have been explored as potential solutions to enhance antibiotic efficacy against the biofilm formation of pathogenic microbes. Quercetin (QER) has previously demonstrated antibacterial and antibiofilm properties.
View Article and Find Full Text PDFBioactive Products Targeting C-Met As Potential Antitumour Drugs.
Anticancer Agents Med Chem
January 2025
Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Unlabelled: Mesenchymal‒epithelial transition factor (c-Met), a receptortyrosine kinase (RTK), plays a vital role in cell proliferation, migration and invasion, and tumour metastasis.
Objective: With increasing duration of treatment, many tumours gradually develop drug resistance. Therefore, novel antitumour drugs need to be developed to treat patients with tumours.
Open frameworks in the NaMn(PO)F fluoro-pyrophosphates system.
Dalton Trans
January 2025
School of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang 212100, Jiangsu, China.
Three new sodium manganese fluoro-pyrophosphate compounds, namely, NaMn(PO)F (I), NaMn(PO)F (II), and NaMn(PO)F (III), have been synthesized by heating a mixture of NaPF, NaPOF or NaHPO with different Mn sources in NaNO and KNO fluxes. The structures of the title compounds were characterized single-crystal X-ray diffraction (XRD). II is characteristic of a shell of Na ions that encloses one [Mn(PO)F] unit, whereas I and III reveal three-dimensional (3D) frameworks that consist of MnO, Mn/NaOF octahedra or MnO octahedra and distorted MnO square pyramids with PO units, where Na cations reside in different-membered ring one-dimensional (1D) tunnels.
View Article and Find Full Text PDFAcid-Base Equilibrium of 5,5,6-Trihydroxy-6-Methyldihydropyrimidine-2,4(1,3)-Dione in the Gas Phase and in Water.
J Phys Chem A
January 2025
Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Laboratory of Physicochemical Methods of Analysis, 69 Prospekt Oktyabrya, Ufa 450054, Russian Federation.
The first-stage acid-base equilibrium of 5,5,6-trihydroxy-6-methyldihydropyrimidine-2,4(1,3)-dione was studied for the first time in aqueous solutions. Its constant (pK = 9.23 ± 0.
View Article and Find Full Text PDFPhysicochemical and sensory characterization of functional synbiotic Labneh fortified with the bacteriocin-producing Lactiplantibacillus plantarum strain GA7 and nano-encapsulated Tirmania pinoyi extract.
Microb Cell Fact
January 2025
Chemistry of Natural and Microbial Products Department, National Research Centre, El Buhouth St., Dokki, Giza, 12311, Egypt.
Background: Functional foods and dairy products are gaining global attention due to their nutritional value and health-promoting characteristics. Lactic acid bacteria (LAB) are one of the promising components included in these products, thanks to their probiotic properties and ability to produce bioactive compounds such as bacteriocins. On the other hand, ectomycorrhizal wild mushrooms (truffles) are known for their ethnomycological importance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!