A New Luminescent Zn(II) Complex: Selective Sensing of CrO and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response.

A novel luminescent coordination polymer (CP) based on Zn(II) ions as nodes [Zn(OPY)(Hbtc)] (1), [Hbtc = trimesic acid and OPY = 4,4'-(oxybis(4,1-phenylene))dipyridine] has been prepared via the solvothermal assembly of a tripodal multicarboxylic acid ligand, a bis-pyridyl ligand with V-shape containing two diverse coordination patterns as well as Zn ion. The experiments of photoluminescence also reflect that the coordination polymer 1 has high sensitivity to potassium dichromate, and its quenching efficiency is K of 2.12 × 10 L·mol. Furthermore, its treatment activity on orthodontic root absorption was evaluated in vivo. Firstly, the CCK-8 assay was performed in this research to evaluate the biotoxicity of the synthetic compound. Next, the TNF-α and Cbfα1 released by the periodontal ligament fibroblast was determined via the ELISA test kit. In addition to this, the signaling pathway of NF-κB activation after treated with compound was measured by the RT-PCR.