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Porcine Epidemic Diarrhea Virus Infection of Porcine Intestinal Epithelial Cells Causes Mitochondrial DNA Release and the Activation of the NLRP3 Inflammasome to Mediate Interleukin-1β Secretion.
Vet Sci
December 2024
Institute of Animal Husbandry and Veterinary Medicine, Jilin Academy of Agricultural Sciences, Kemao Street No. 186, Gongzhuling 136100, China.
Porcine epidemic diarrhea virus (PEDV) induces enteritis and diarrhea in piglets. Mitochondrial DNA (mtDNA) contributes to virus-induced inflammatory responses; however, the involvement of inflammasomes in PEDV infection responses remains unclear. We investigated the mechanism underlying inflammasome-mediated interleukin (IL)-1β secretion during the PEDV infection of porcine intestinal epithelial (IPEC-J2) cells.
View Article and Find Full Text PDFSystemic Granulomatosis in the Meagre : Fishing for a Plausible Etiology.
Vet Sci
November 2024
Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Meagre () is one of the fast-growing species considered for sustainable aquaculture development along the Mediterranean and Eastern Atlantic coasts. The emergence of Systemic Granulomatosis (SG), a disease marked by multiple granulomas in various tissues, poses a significant challenge in meagre aquaculture. In the current study, we investigate the association of spp.
View Article and Find Full Text PDFEffects of Acute Salinity Stress on the Histological and Bacterial Community Structure and Function in Intestine of .
Mar Drugs
December 2024
Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
This study focused on and conducted stress experiments at salinity levels of 20‱ and 40‱. Intestinal histological changes and the structural characteristics of the intestinal flora of under salinity stress were analyzed. The results show that acute salinity stress inflicts varying degrees of damage to the intestinal tissues of .
View Article and Find Full Text PDFFoundational Image Analyses for Ultrasonographic Screening of Abdominal Aortic Aneurysm.
Ann Vasc Dis
December 2024
Department of Anesthesiology, Kochi Medical School, Nankoku, Kochi, Japan.
With improved surgical outcomes for non-ruptured abdominal aortic aneurysm (AAA), the primary objective has shifted toward the detection of asymptomatic AAA. Since ultrasonographic visualization from the anterior abdominal wall is often obstructed by intestinal gas, utilizing additional bilateral posterior approaches via the retroperitoneal tissue may be beneficial. This study investigates the feasibility of assessment using three approaches through computed tomography (CT) data analyses.
View Article and Find Full Text PDFSmall intestine neuroendocrine tumours (SI-NETs) are often diagnosed late with a UK median of 3 years and high misdiagnosis rates. Previous studies, largely based on patient surveys, offer little data on improving diagnosis. In 2017, the South Wales NET service underwent a nationally commissioned, systematic transformation, aiming to improve diagnosis through the development of a gastroenterology and surgical referral network, and education of these specialities.
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