Report of Four Cases of Endogenous Endophthalmitis Originated from Liver Abscess with Eye Complaints as the Initial Presentations.

Purpose: To report four cases of endogenous endophthalmitis (EE) secondary to liver abscess, and discuss their clinic features and outcomes.

Methods: Clinical data were collected by reviewing the medical records of four patients diagnosed with endogenous endophthalmitis (EKPE) secondary to liver abscess.

Results: Four patients were diagnosed with EE. Two males and two females, with ages ranging from 33 to 63 years old. All patients presented with ocular symptoms initially. Liver abscesses were diagnosed during hospitalization. All cases were caused by Klebsiella Pneumoniae confirmed by blood or tissue cultures. All patients were treated with intravitreal antibiotic injection, and two of the patients had vitrectomy. At the end, all affected eyes underwent evisceration. One patient died of septic shock with multiple organ failures.

Conclusion: EE secondary to liver abscess with metastatic spread is a severe sight-threatening condition. The delayed discovery of liver abscess may hinder the diagnosis and treatment of the disease, which may be related to poor prognosis.