Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) enables spatially resolved quantitative measurements of major, minor and trace element abundances in igneous rocks and minerals with equal or better precision than many other in situ techniques, and more rapidly than labour-intensive wet chemistry procedures. Common applications for LA-ICP-MS in the Earth sciences centre on investigating the composition of natural and experimental geological materials, including: analysis of whole rock silicate glasses, flux-free pressed powder tablets and/or fused aliquots of materials; in situ probing of individual minerals, xenocrysts, fluid and melt inclusions, experimental run products, and siderophile-rich micronuggets; and multidimensional chemical mapping of complex (multiphase) materials.
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http://dx.doi.org/10.2113/gselements.12.5.311 | DOI Listing |
Int J Mol Med
March 2025
Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Iron metabolism plays a crucial role in the tumor microenvironment, influencing various aspects of cancer cell biology and tumor progression. This review discusses the regulatory mechanisms of iron metabolism within the tumor microenvironment and highlights how tumor cells and associated stromal cells manage iron uptake, accumulation and regulation. The sources of iron within tumors and the biological importance of ferroptosis in cancer were explored, focusing on its mechanisms, biological effects and, in particular, its tumor‑suppressive properties.
View Article and Find Full Text PDFJ Appl Lab Med
January 2025
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Background: Laboratory stewardship programs are increasingly adopted to enhance test utilization and improve patient care. Despite their potential, implementation within complex healthcare systems remains challenging. Benchmarking metrics helps institutions compare their performance against peers or best practices.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Background: The fracture of an endodontic instrument within the root canal system can occur during root canal therapy, complicating thorough cleaning and shaping. Consequently, managing the broken fragment becomes crucial.
Methods: Eighty Nickel-titanium (NiTi) #20 K-files (Mani, Tochigi, Japan) were cut 8 mm from the tip, fixed into a corkboard, and classified into five groups (n = 14 each).
BMC Plant Biol
January 2025
Department of Crop Sciences, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Purpose: This study explored how exogenous silicon (Si) affects growth and salt resistance in maize.
Methods: The maize was cultivated in sand-filled pots, incorporating varied silicon and salt stress (NaCl) treatments. Silicon was applied at 0, 2, 4, 6, and 8 mM, and salt stress was induced using 0, 60 and120 mM concentrations.
Sci Rep
January 2025
Departments of Gastrointestinal Surgery, Affiliated Hospital of Guangdong Medical University, No. 57, South of Renmin Avenue, Zhanjiang, 524001, Guangdong Province, China.
We aimed to explore the role of circular RNA 0043256 (circ_0043256) in gastric cancer (GC) and its underlying mechanisms. The impact of circ_0043256 silencing on the proliferation, migration, apoptosis, and aerobic glycolysis of MKN-45 and AGS cells induced by CoCl2 was assessed through the utilization of CCK-8, wound healing assay, flow cytometry, and metabolic analysis. The interaction between circ_0043256 and miR-593-5p, as well as the involvement of the miR-593-5p/RRM2 axis in gastric cancer, were confirmed via luciferase assay, Western blot, and bioinformatics analysis.
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