This systematic review aimed to discuss the effects of arginine on caries-related microorganisms in different biofilm models. The eligibility criteria were studies that evaluated the effect of arginine at different concentrations on caries-related microorganisms using biofilm models. Eighteen studies published between 2012 and 2019 were included. Different bacterial species were studied. Seventeen studies (94.4%) achieved a low risk of bias and only one showed a medium risk of bias. The studies showed that arginine is a promising approach for the ecological management of dental caries. The focus of this review was to evaluate the effects of arginine on microorganisms involved in the mechanism of dental caries.
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| http://dx.doi.org/10.1080/08927014.2020.1802587 | DOI Listing |
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