In this paper, we propose a coupled-double-photonic-crystal-slab (CDPCS) sensor for simultaneously detecting refractive index (RI) and temperature (T) with high accuracy and strong anti-interference ability, using transverse magnetic-like (TM-like) mode and transverse electric-like (TE-like) mode. Based on the temporal coupled-mode theory, the theoretical model of the structure is established and the transmission formula is derived. The agreement between the theoretical and the simulated transmission spectra is proved. In order to achieve both high quality (Q)-factor and high modulation depth, the structure is optimized by adjusting the geometric parameters. The Q-factors of both TM-like mode and TE-like mode reach a magnitude order of 10. For the dual-parameter sensing, high RI sensitivities of 960 nm/RIU and 210 nm/RIU, and T sensitivities of -66.5 pm/K and 50.75 pm/K, are obtained for TM-like mode and TE-like mode, respectively. The relative deviations of RI and T sensing are as low as 0.6% and 1.0%, respectively, indicating high detection accuracy. Even considering the influence of external interference, the sensor can effectively resist external interference. The proposed CDPCS sensor has remarkable performance improvements in sensitivity, Q-factor, detection accuracy, and anti-interference ability. This study shows great potential in on-chip sensing and multi-parameter detection.
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http://dx.doi.org/10.1364/OE.391680 | DOI Listing |
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December 2024
School of Chemistry, GDMPA Key Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, South China Normal University, Guangzhou, 510006, China.
Green and efficient total antioxidant capacity (TAC) detection is significant for healthy diet and disease prevention. This work first proposed the concept of TAC colorimetric detection based on microrobots. A novel metal-organic framework (MOF)-based biomimetic enzyme microrobot (MIL-88A@FeO) is developed that can efficiently and accurately detect the TAC of real fruits and vegetables.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2024
Department of Polymeric Materials and Engineering, School of Materials and Energy, Guangdong University of Technology, Guangzhou 510006, China. Electronic address:
High copper levels pose a risk to environmental and human health due to their toxicity and widespread industrial application, in which abnormal copper levels are associated with various diseases both in neurodegenerative diseases and plant growth. Thus, a turn-on fluorescent probe BBYD-Cu, based on donor-acceptor type structure, was designed and synthesized with easy preparations. BBYD-Cu can specifically recognized Cu by 2-picolinic ester group, then released the fluorophore to enhance the fluorescent signals.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Health Science and Engineering, Shanghai Engineering Research Center of Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai 200093, China. Electronic address:
Aptamer conformations are susceptible to environmental conditions, which makes it difficult to achieve stable targets detection in complex environments with aptasensors. Imprinting strategy was proposed to immobilize the specific conformation of aptamers, aiming to enhance their recognition anti-interference. However, it is mechanistically unclear how the imprinted polymers affect aptamers' recognition, which limits application of the strategy.
View Article and Find Full Text PDFAnal Chem
December 2024
Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China.
is one of the most dangerous and contagious foodborne pathogens, posing a significant threat to public health and food safety. In this study, we developed a click chemistry-based fluorescence biosensing platform for highly sensitive detection of () by integrating the -cleavage activity of CRISPR/Cas12a with the CLICK17-mediated copper(II)-dependent azide-alkyne cycloaddition (Cu(II)AAC) click reaction. Herein, CLICK-17 can provide binding sites for Cu ions and high redox stability for one or much catalytically vital Cu within its active sites, which facilitate the click reaction.
View Article and Find Full Text PDFTalanta
December 2024
Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, PR China. Electronic address:
Exosomes, extracellular vesicles crucial for intercellular communication, are emerging as significant biomarkers for disease diagnosis, especially in cancer. This study presented a dual-mode exosome detection platform using polydopamine microspheres doped with iron and zinc ions (PDA@Fe@Zn). These materials served as both artificial receptors for nucleic acid aptamers and nanozymes with peroxidase-like activity.
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