Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center.

Diagnostics (Basel)

Department of Obstetrics and Gynecology, University Clinic of Carl Gustav Carus Dresden, Technische Universität Dresden, 01307 Dresden, Germany.

Published: July 2020

AI Article Synopsis

  • The study aimed to identify prenatal indicators to predict complications or surgical needs in fetuses with gastroschisis, improving parental counseling and delivery planning.
  • It analyzed 34 cases of gastroschisis from 2007 to 2017, finding 22 cases of simple and 11 of complex gastroschisis.
  • A specific measurement of intraabdominal bowel dilatation (IABD) at 18 mm was highly effective in predicting simple gastroschisis, whereas extra-abdominal bowel dilatation (EABD) had lower reliability for complex cases.

Article Abstract

The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the timing of delivery and therapy. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 34 cases of gastroschisis between the years 2007 and 2017. A total of 34 fetuses with gastroschisis were examined and 33 outcomes registered: 22 cases of simple gastroschisis (66.7%) and 11 cases of complex gastroschisis (33.3%). A cut-off value of 18 mm for intraabdominal bowel dilatation (IABD) showed a positive predictive value (PPV) of 100% for predicting simple gastroschisis. IABD gives the best prediction for simple versus complex gastroschisis (cut-off of 18 mm). Extra-abdominal bowel dilatation (EABD) cut-off values of 10 mm and 18 mm showed low sensitivity and specificity to predict complex gastroschisis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460378PMC
http://dx.doi.org/10.3390/diagnostics10080540DOI Listing

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