A 63-year-old man presented with imbalance when coughing due to a respiratory tract infection. He had a history of multiple myeloma with a plasmacytoma of the left temporal bone. Examination revealed a positive leftward head impulse test, no spontaneous nystagmus, left-beating positional nystagmus, and left-beating Valsalva-induced nystagmus. Videonystagmography, audiology, and comprehensive vestibular function tests revealed a subtotal left peripheral audio-vestibular loss. Temporal bone computed tomography showed an unchanged bony erosion of the left labyrinth from 2 years prior. Vertigo subsided after treatment of the respiratory tract infection. Although no tumor progression was evident, coughing had triggered a preexisting third mobile window to declare itself. Laryngoscope, 131:E966-E969, 2021.
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http://dx.doi.org/10.1002/lary.28951 | DOI Listing |
Ear Nose Throat J
January 2025
Department of Otolaryngology, Northern Jiangsu People's Hospital, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, PR China.
This study aimed to compare the efficacy of continuous perfusion of underwater bone grinding combined with a -shaped incision versus a microscopic posterior ear incision in the treatment of attic cholesteatoma. Clinical trials were prospective studies from the Northern Jiangsu People's Hospital. Adult patients with middle ear cholesteatoma requiring ear surgery agreed to participate between September 2019 and September 2023 (age > 18).
View Article and Find Full Text PDFJ Adv Res
December 2024
State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address:
Introduction: The periodontal ligament (PDL), a dynamic connective tissue that anchors teeth to the alveolar bone, enables tooth retention and facilitates continuous turnover. The integrity of the periodontium is maintained by periodontal ligament stem cells (PDLSCs), whose dysfunction and senescence with age can disrupt tissue homeostasis, hinder injury repair, and lead to tooth loss, ultimately impacting overall health. Transforming growth factor-β1 (TGF-β1) is known for its regenerative properties and as a functional paracrine factor in stem cell therapy, but its precise role in modulating PDLSC activity remains controversial and poorly understood.
View Article and Find Full Text PDFAm J Otolaryngol
December 2024
Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Purpose: To compare the performance of the photon-counting detector (PCD)-CT versus a state-of-the-art energy-integrating detector (EID)-CT to identify segments of the inferior tympanic canaliculus (Jacobsons nerve) and the mastoid canaliculus (Arnolds nerve).
Materials & Methods: Patients were prospectively recruited to undergo temporal bone CT on both EID-CT (Siemens Somatom Force) and PCD-CT (Siemens NAEOTOM Alpha) scanners under an IRB-approved protocol. Three neuroradiologists reviewed cases by consensus comparing the ability to identify the proximal, mid, and distal segments of the inferior tympanic canaliculus/Jacobsons nerve and mastoid canaliculus/Arnolds nerve on each scanner using 5-point Likert scales (with 1 indicating EID is far superior to PCD, 3 indicating they are equivalent, and 5 indicating PCD is far superior to EID).
Laryngoscope
December 2024
Division of Otolaryngology - Head & Neck Surgery, Cooper University Health Care, Camden, New Jersey, U.S.A.
Objective(s): To compare the incidence of acute and chronic complications of temporal bone fractures, and identify predictors for post-injury, audiometrically confirmed hearing loss.
Methods: Retrospective cohort analysis of patients with acute temporal bone fractures who underwent both in-hospital and outpatient follow-up Otolaryngology evaluation at an academic, tertiary-care institution from January 2002 to January 2023. Otologic outcomes were compared between initial and follow-up evaluations.
Eur Arch Otorhinolaryngol
December 2024
Departments of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, School of Medicine, Tel Aviv Sourasky Medical Center, Tel-Aviv University, Tel Aviv, 6423907, Israel.
Objective: To characterize middle ear (ME) effusion still present 2 months after repair surgery for spontaneous cerebrospinal fluid (CSF) leak via the temporal bone (TB).
Study Design: A retrospective chart review (2011-2022).
Setting: Tertiary referral academic center.
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