The coronavirus disease 2019 (COVID-19) pandemic spread by the single-stranded RNA severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the seventh generation of the coronavirus family. Following an unusual replication mechanism, its extreme ease of transmissivity has put many countries under lockdown. With the uncertainty of developing a cure/vaccine for the infection in the near future, the onus currently lies on healthcare infrastructure, policies, government activities, and behaviour of the people to contain the virus. This research uses exponential growth modelling studies to understand the spreading patterns of SARS-CoV-2 and identifies countries that showed early signs of containment until March 26, 2020. Predictive supervised machine learning models are built using infrastructure, environment, policies, and infection-related independent variables to predict early containment. COVID-19 infection data across 42 countries are used. Logistic regression results show a positive significant relationship between healthcare infrastructure and lockdown policies, and signs of early containment. Machine learning models based on logistic regression, decision tree, random forest, and support vector machines are developed and show accuracies between 76.2% and 92.9% to predict early signs of infection containment. Other policies and the decisions taken by countries to contain the infection are also discussed.
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http://dx.doi.org/10.1111/tbed.13764 | DOI Listing |
J Formos Med Assoc
January 2025
Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung Shan S. Rd.(Zhongshan S. Rd.), Zhongzheng Dist., Taipei City, 100225, Taiwan, ROC; College of Medicine, National Taiwan University, No.1 Jen Ai road section 1, Taipei 100, Taiwan, ROC. Electronic address:
The coronavirus Disease 2019 (COVID-19) pandemic has disproportionately impacted long-term care facilities (LTCFs), revealing vulnerabilities due to residents' advanced age, comorbidities, and facility infrastructures. In Taiwan, the Central Epidemic Control Center implemented a range of strategies to protect LTCF residents. These included early containment measures to allow time for preparing pharmaceutical intervention, the establishment of infection prevention and control guidelines, the implementation of comprehensive screening and testing protocols, the prioritization of vaccination for both residents and staff, and the expansion of the national stockpile of oral antiviral agents.
View Article and Find Full Text PDFSci Total Environ
December 2024
Department of Civil & Environmental Engineering & Earth Sciences, University of Notre Dame, Notre Dame, IN 46556, United States of America. Electronic address:
Measles is a highly transmissible disease of increasing concern due to waning vaccination contributing to a significant rise in measles cases, with 283 reported cases and 16 outbreaks in the U.S. as of November 7, 2024.
View Article and Find Full Text PDFPNAS Nexus
December 2024
Pfizer, 66 Hudson Boulevard, New York, NY 10018, USA.
Our world is ever evolving and interconnected, creating constant opportunities for disease outbreaks and pandemics to occur, making pandemic preparedness and pathogen management crucial for global health security. Early pathogen identification and intervention play a key role in mitigating the impacts of disease outbreaks. In this perspective, we present the Viral Trait Assessment for Pandemics (ViTAP) model to aid in the early identification of high-risk viruses that have pandemic potential, which incorporates lessons from past pandemics, including which key viral characteristics are important such as genetic makeup, transmission modes, mutation rates, and symptom severity.
View Article and Find Full Text PDFPLoS One
December 2024
School of Economics and Finance, Queensland University of Technology, Brisbane, QLD, Australia.
Evidence from clinical research suggests that in the first two waves of COVID-19, the virus spread rapidly through a large number of undocumented asymptomatic infections. These 'silent' infections camouflaged the actual incidence of the disease, leading to downward biases in the rates of transmission, disease prevalence, and fatality. These, in turn, had implications for how people and policymakers responded to changing infection prevalence.
View Article and Find Full Text PDFPest Manag Sci
December 2024
Southern Breeding Administrate Office of Hainan Province, Sanya, China.
Background: Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus (MDMV) infections severely affect corn productivity worldwide. Rapid point-of-need diagnoses of quarantine pathogens P.
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