AI Article Synopsis
- Richter syndrome is a serious condition where chronic lymphocytic leukemia turns into a type of lymphoma, usually with a bad outlook for patients.
- A rare case was reported about a 72-year-old man who had Richter syndrome affecting his testicles and noticed swelling there.
- Quick diagnosis and treatment with specific medications can help improve the chances of survival for patients with this rare type of Richter syndrome.
Article Abstract
Introduction: Richter syndrome refers to the transformation from chronic lymphocytic leukemia to assaultive lymphoma, often a diffuse large B-cell lymphoma, and has a greatly poor prognosis. Richter syndrome is characterized by rapidly growing lymphadenopathy but rarely presents with extra-nodal involvement, common sites being the digestive tract, lungs, kidneys, and central nervous system. However, Richter syndrome with testicular involvement is extremely rare.
Case Presentation: Herein we report a very scare case of a male at the age of 72 with Richter syndrome and testicular involvement, diagnosed by the investigation of bilateral scrotal swellings. The patient had attained disease-free survival for over a year with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone, and the intrathecal administration of chemotherapeutic agents after diagnosis by immediate orchiectomy.
Conclusion: An early pathological diagnosis by immediate orchiectomy and the early initiation of induction immunochemotherapy may be good prognostic factors in Richter syndrome involving the testes.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292090 | PMC |
| http://dx.doi.org/10.1002/iju5.12096 | DOI Listing |
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