Clear cell adenocarcinoma of the prostatic urethra: A case report.

Introduction: Clear cell adenocarcinoma of the prostatic urethra in men is an extremely rare disease, with only eight case reports published.

Case Presentation: A 56-year-old man visited our hospital for gross hematuria. Urinary cytology detected class V, cystoscopy showed no abnormal findings, and contrast-enhanced computed tomography also showed no abnormal findings in his upper urinary tract except for a low-enhancement lesion on his left prostate lobe. Magnetic resonance imaging revealed a cystic lesion surrounding the prostate that was suspected of being urethral or prostate cancer, so transurethral resection was performed. A papillary tumor was detected at the prostatic urethra, and after resecting this tumor, a cavity showing multiple tumors was observed. The final pathological diagnosis was clear cell adenocarcinoma. Laparoscopic radical cystectomy and urethrectomy were thus performed. The pathological diagnosis was the same as at the primary tumor site.

Conclusion: We herein report a case of clear cell adenocarcinoma of the prostatic urethra.