Aim And Objective: The aim of this study was to evaluate and compare the antifungal efficacy of MTA Fillapex, Metapex, zinc oxide eugenol cement, Endomethasone, and Endoflas against .
Materials And Methods: Root canal exudates of 30 patients were tested against MTA Fillapex (Angelus), Metapex (BioMed), zinc oxide eugenol (Deepak Enterprise), Endomethasone (Septodont), Endoflas FS (Sanlor Laboratories), MTA (Angelus) (positive control), and glycerine (negative control). Children with failed endodontic cases were included in the study. Tube dilution and agar diffusion methods were used to check the antifungal efficacy of the root canal sealers. In tube dilution method, 24-well culture plates containing freshly mixed material along with were used. Wells containing MTA (Angelus) along with Sabouraud dextrose agar and served as positive control while glycerine along with Sabouraud dextrose agar and served as negative control. All plates were incubated at 37°C for 24 hours. Growth of the fungi was monitored after 24 hours by the presence of the turbidity. The samples were recultured to test the experimental material using agar well diffusion method, and the Petri plates were incubated for 24 hours and 72 hours. Zone of inhibition was measured after respective time period. Paired test was used for the data analysis.
Results: It was seen in tube dilution method Endomethasone showed least turbidity while maximum was shown by Metapex; similar results were seen in case of agar well diffusion method in which largest zone of inhibition was shown by Endomethasone while smallest was by Metapex.
Conclusion: It was concluded that Endomethasone showed maximum efficacy against as compared to Metapex.
How To Cite This Article: Singh S, Srivastava B, Gupta K, Comparative Evaluation of Antifungal Efficacy of Five Root Canal Sealers against Clinical Isolates of : A Microbiological Study. Int J Clin Pediatr Dent 2020;13(2):119-123.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366757 | PMC |
| http://dx.doi.org/10.5005/jp-journals-10005-1718 | DOI Listing |
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