AI Article Synopsis
- Tubular functions play a key role in maintaining homeostasis, but are often overlooked in clinical assessments.
- Recent research indicates that baseline tubular dysfunction can increase the risk of acute kidney injury (AKI), regardless of other kidney function markers like glomerular filtration rate and albumin levels.
- The study explores the differences between tubular function changes and kidney injury before and after an AKI episode, providing important biological insights.
Article Abstract
Tubular functions are critical for homeostasis maintenance. However, tubular function markers are not typically assessed in routine clinical care. Recent research by our group has revealed that tubular dysfunction at baseline is a risk factor for subsequent acute kidney injury (AKI), independent of estimated glomerular filtration rate and albuminuria. Here, we describe the underlying hypotheses and biological insights and contrast the changes in tubule function versus injury both before and after an AKI episode.
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| http://dx.doi.org/10.1159/000508697 | DOI Listing |
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