AI Article Synopsis

  • * It shows potential as a neuroprotective agent, with positive effects noted in preclinical studies for diseases like Alzheimer’s, Parkinson’s, and Huntington’s.
  • * Despite its promising preclinical activities, the clinical trial research on myricetin as a nutraceutical is still limited, highlighting the need for further investigation.

Article Abstract

Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395214PMC
http://dx.doi.org/10.1186/s12906-020-03033-zDOI Listing

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