New core configuration for the fabrication of I radioactive sources for cancer treatment.

Appl Radiat Isot

Instituto de Pesquisas Energéticas e Nucleares, Cidade Universitária, Avenida Professor Lineu Prestes, 2242 Zip-code: 05508-000, São Paulo, SP, Brazil. Electronic address:

Published: November 2020

AI Article Synopsis

  • IPEN is constructing a lab to produce radioactive sources for prostate brachytherapy to increase treatment accessibility in Brazil.
  • A new production method for iodine-125 seeds has been developed, achieving a yield of 71.7% ± 5.3%, taking into account factors like photo-sensibility and reaction vial type.
  • Advanced analysis methods like FTIR and EDS were used, and a Monte Carlo-MCNP6 simulation was conducted to assess TG-43 parameters for the new seeds.

Article Abstract

In order to provide prostate brachytherapy treatment for more Brazilian men, IPEN is building a laboratory for the manufacture of radioactive sources. The new methodology for the production of iodine-125 seeds with yield 71.7% ± 5.3%. Points of importance were evaluated/discussed: photo-sensibility, reaction vial type, the substitution for iodine-131, pH, and solution volume. The surface was analyzed by FTIR and EDS. At the end, a Monte Carlo-MCNP6 simulation was performed to evaluate the TG-43 parameters.

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Source
http://dx.doi.org/10.1016/j.apradiso.2020.109307DOI Listing

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