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Exposure to 6PPD-Q induces dysfunctions of ovarian granulosa cells: Its potential role in PCOS.
J Hazard Mater
December 2024
Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China. Electronic address:
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q), an environmental pollutant derived from the ozonolysis of the widely used tire rubber antioxidant 6PPD, has been found to accumulate in air, dust, and water, posing significant health risks. While its reproductive toxicity in male organisms has been established, its effects on female reproductive health remain unclear. Polycystic ovary syndrome (PCOS), a common endocrine disorder in premenopausal women, is known to be influenced by environmental pollutants.
View Article and Find Full Text PDFRegion-specific roles of oviductal motile cilia in oocyte/embryo transport and fertility.
Biol Reprod
January 2025
Department of Integrative Physiology, Baylor College of Medicine, Houston, TX USA.
The physiological and clinical importance of motile cilia in reproduction is well recognized, however, the specific role they play in transport through the oviduct and how ciliopathies lead to subfertility and infertility is still unclear. The contribution of cilia beating, fluid flow, and smooth muscle contraction to overall progressive transport within the oviduct remains under debate. Therefore, we investigated the role of cilia in the oviduct transport of preimplantation eggs and embryos using a combination of genetic and advanced imaging approaches.
View Article and Find Full Text PDFCommunication Skills in Toddlers Exposed to Maternal SARS-CoV-2 during Pregnancy.
Life (Basel)
September 2024
Audiology, Primary Care Department, AUSL of Modena, 41100 Modena, Italy.
Studies about the effects of SARS-CoV-2 on pregnant women and children born to positive women are controversial with regard to possible inner ear-related damage but most of them do not detect the involvement of this virus in auditory function. However, only a few studies on long-term effects on language development are currently available because of the recent onset of the pandemic. The aim of this study was to investigate the impact of SARS-CoV-2 infection on perceptual and expressive abilities and the emerging development of communication in young children.
View Article and Find Full Text PDF[Call attention to the reproductive disorders of chronic endometritis].
Zhonghua Yi Xue Za Zhi
October 2024
Reproductive Medical Center, Department of Gynecology and Obstetrics, Peking University Third Hospital, Beijing 100191, China.
Chronic endometritis (CE) is an important factor leading to decreased endometrial receptivity, infertility, and repeated pregnancy loss; endometrial immune dysfunction, abnormal microbial flora, inflammatory status, and other factors play important roles in the occurrence and development of CE. Meanwhile, these factors are closely related to the pathophysiological mechanisms of common diseases that cause infertility, such as endometriosis, polycystic ovary syndrome, tubal diseases, and endometrial polyps. Through further development of high-quality prospective clinical research, microbiome and immunomics of CE and endometriosis,polycystic ovary syndrome and other diseases, to provide a new therapeutic idea for the treatment of refractory CE.
View Article and Find Full Text PDFA Prospective Comparative Study of Impedance Audiometry Findings Preoperatively and Postoperatively in Cases of Conventional Adenoidectomy versus Microdebrider Assisted Adenoidectomy.
Indian J Otolaryngol Head Neck Surg
October 2024
Department of ENT, Tata Main Hospital & Manipal Tata Medical College, Jamshedpur, Jharkhand India.
The aim of the study was to evaluate and compare the efficacy of Endoscopic Adenoidectomy with Microdebrider over Conventional technique by Curettage using Impedance Audiometry findings. In this prospective, randomised, comparative study patients were divided into two groups to undergo one of the above adenoidectomy surgeries. Patients with symptoms of Adenoid hypertrophy after failed maximal medical therapy (12 weeks) were selected after due consideration of the inclusion and exclusion criteria.
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