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Objective: This study investigated the role of specialty concussion care on the clinical course of recovery in adolescent patients who initiated care beyond 3 weeks from their injury.

Design: Retrospective analysis of protracted recovery groups was based on the number of days in which a patient presented for care postinjury: early (22-35 days), middle (36-49 days), and late (50+ days).

Setting: Sports medicine and orthopedics clinic.

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  • * In Rivers State, the prevalence of stroke is notably higher than the national average, highlighting the urgent need to understand in-hospital mortality predictors for AIS patients.
  • * A study conducted at the University of Port-Harcourt Teaching Hospital over ten months aimed to identify factors influencing short-term mortality in AIS patients using clinical assessments and statistical analysis.
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Background: Stroke chameleons (SC), are often diagnosed too late in their course to benefit from intravenous thrombolysis (IVT) treatment in the Emergency Room (ER). It remains unclear what proportion of this patient population would be a candidate for IVT. We sought to identify the proportion of SC patients with contraindications to IVT and to delineate what those contraindications are.

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  • The study focuses on three siblings with severe early-onset neurological issues linked to compound heterozygous variants in a specific gene, highlighting symptoms like muscular hypotonia, seizures, and apnoea.
  • Two of the siblings died young, with suspected causes related to their conditions, while the third sibling developed epilepsy and mild intellectual impairment.
  • Genetic testing revealed both maternal and paternal pathogenic variants associated with the severe phenotype of developmental epileptic encephalopathy (DEE), emphasizing the need for further research to understand unusual clinical cases related to these genetic disorders.
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Endogenous pain modulation after sleep restriction in migraine: a blinded crossover study.

J Headache Pain

October 2024

Department of Neuromedicine and Movement Sciences, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, 7491, Norway.

Background: Patients with migraine are vulnerable to insufficient sleep, but the impact of sleep restriction is largely unknown. In addition, the importance of sleep may be different in patients with migraine who mostly have attack onsets during sleep, so called sleep-related migraine, compared to patients with non-sleep-related migraine. In this study we investigate the effect of sleep restriction on endogenous pain modulation in patients with migraine and healthy controls.

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