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<PubmedArticle><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32733782</PMID><DateRevised><Year>2024</Year><Month>03</Month><Day>29</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Print">2196-5226</ISSN><JournalIssue CitedMedium="Print"><Volume>15</Volume><PubDate><Year>2020</Year></PubDate></JournalIssue><Title>GMS hygiene and infection control</Title><ISOAbbreviation>GMS Hyg Infect Control</ISOAbbreviation></Journal><ArticleTitle>Seroprevalence of COVID-19 antibodies in the cleaning and oncological staff of a municipal clinic.</ArticleTitle><Pagination><StartPage>Doc18</StartPage><MedlinePgn>Doc18</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">Doc18</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3205/dgkh000353</ELocationID><Abstract><AbstractText><b>Aim:</b> To prevent shedding of the novel COVID-19 virus in hospitals, strict hygiene measures and surveillance of the staff and patients is mandatory. Studying the available literature, we assumed that monitoring of the cleaning staff may sometimes be a "blind spot" in surveillance. Although the cleaning personnel is not entrusted with the medical and nursing care of patients, the extent of patient contacts in this group may be comparable to medical personnel and even increase in times of a visit ban in many hospitals. The aim of this study was to investigate the prevalence of COVID-19 infections already undergone in this group. <b>Methods:</b> Antibody titers (IgA and IgG) against COVID-19 were measured in the cleaning staff from June 15<sup>th</sup> to 30<sup>th</sup>, 2020 in our clinic. Antibodies against COVID-19 were determined using ELISA (EUROIMMUN&#x2122;, PerkinElmer, Inc. Company). For purposes of comparison, the same procedure was performed in the staff of the oncology ward, who were regarded as an important group due to their high-risk patients. <b>Results:</b> During the study period, 45 members of the cleaning staff and 20 members of the oncology ward were tested. Significantly elevated IgA antibody titers were detected in 1 person in the first group and in 1 person in the second group. Significantly elevated IgG antibody titers were not detected in the first group and in 1 person of the second group. In case of positive or indeterminate testing, swabs for direct virus detection were taken, but were negative in all cases. <b>Conclusion:</b> The prevalence of already undergone infections in both groups is low, as to be expected due to the still low incidence of COVID-19 infections in the German federal state of Thuringia. However, the presence of such antibodies in the cleaning personnel demonstrates the need for equally strict surveillance in this group.</AbstractText><CopyrightInformation>Copyright &#xa9; 2020 Epstude et al.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Epstude</LastName><ForeName>J&#xf6;rg</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Hospital Hygiene, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harsch</LastName><ForeName>Igor Alexander</ForeName><Initials>IA</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine II, Thuringia Clinic "Georgius Agricola", Saalfeld/Saale, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>GMS Hyg Infect Control</MedlineTA><NlmUniqueID>101609519</NlmUniqueID><ISSNLinking>2196-5226</ISSNLinking></MedlineJournalInfo><OtherAbstract Type="Publisher" Language="ger"><AbstractText><b>Einleitung:</b> Um die Verbreitung des neuartigen COVID-19-Virus in Krankenh&#xe4;usern zu verhindern, sind strenge Hygienema&#xdf;nahmen und die &#xdc;berwachung des Personals und der Patienten obligatorisch. Nach Sichtung der verf&#xfc;gbaren Literatur entsteht der Eindruck, dass die &#xdc;berwachung des Reinigungspersonals manchmal ein &#x201e;blinder Fleck&#x201c; bei der &#xdc;berwachung ist. Obwohl das Reinigungspersonal nicht mit der medizinischen und pflegerischen Versorgung der Patienten betraut ist, kann das Ausma&#xdf; der Patientenkontakte in dieser Gruppe mit denen der Pflege vergleichbar sein und in Zeiten eines Besuchsverbots in vielen Krankenh&#xe4;usern sogar zunehmen. Ziel dieser Studie war es, die Pr&#xe4;valenz bereits &#xfc;berstandener COVID-19-Infektionen in dieser Gruppe zu untersuchen.<b>Methoden:</b> Die Antik&#xf6;rpertiter (IgA und IgG) gegen COVID-19 wurden beim Raumpflegepersonal vom 15. bis 30. Juni 2020 in unserer Klinik bestimmt. Die Antik&#xf6;rperbestimmung gegen COVID-19 wurde mit einem ELISA (EUROIMMUN<sup>TM</sup>, PerkinElmer, Inc. Company) durchgef&#xfc;hrt. Zu Vergleichszwecken wurde bei den Mitarbeitern der Onkologiestation das gleiche Procedere vorgenommen, da wir diese Mitarbeiter aufgrund ihrer Hochrisikopatienten als ebenfalls f&#xfc;r eine &#xdc;berwachung wichtige Gruppe betrachteten.<b>Ergebnisse:</b> W&#xe4;hrend des Studienzeitraums wurden 45 Mitarbeiter des Raumpflegepersonals und 20 Mitglieder der Onkologiestation getestet. Signifikant erh&#xf6;hte IgA-Antik&#xf6;rpertiter wurden in beiden Gruppen bei je 1 Person nachgewiesen. Signifikant erh&#xf6;hte IgG-Antik&#xf6;rpertiter wurden in der ersten Gruppe nicht und in der zweiten Gruppe bei 1 Person nachgewiesen. Bei positiven und grenzwertigen Tests wurden Abstriche f&#xfc;r einen direkten Virusnachweis entnommen, die jedoch in allen F&#xe4;llen negativ waren.<b>Diskussion:</b> Die Pr&#xe4;valenz bereits durchgemachter Infektionen ist in beiden Gruppen gering, was aufgrund der noch geringen Inzidenz von COVID-19-Infektionen im Bundesland Th&#xfc;ringen zu erwarten war. Das Vorhandensein solcher Antik&#xf6;rper beim Raumpflegepersonal zeigt jedoch, dass auch in dieser Gruppe eine strikte &#xdc;berwachung sinnvoll ist.</AbstractText><CopyrightInformation>Copyright &#xa9; 2020 Epstude et al.</CopyrightInformation></OtherAbstract><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword><Keyword MajorTopicYN="N">antibodies</Keyword><Keyword MajorTopicYN="N">cancer</Keyword><Keyword MajorTopicYN="N">cleaning personnel</Keyword><Keyword MajorTopicYN="N">cleaning staff</Keyword><Keyword MajorTopicYN="N">hospital hygiene</Keyword><Keyword MajorTopicYN="N">oncology</Keyword><Keyword MajorTopicYN="N">serology</Keyword></KeywordList><CoiStatement>The authors declare that they have no competing interests.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>1</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="pmc-release"><Year>2020</Year><Month>7</Month><Day>23</Day></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32733782</ArticleId><ArticleId IdType="pmc">PMC7376972</ArticleId><ArticleId IdType="doi">10.3205/dgkh000353</ArticleId><ArticleId IdType="pii">dgkh000353</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Korth J, Wilde B, Dolff S, Anastasiou OE, Krawczyk A, Jahn M, Cordes S, Ross B, Esser S, Lindemann M, Kribben A, Dittmer U, Witzke O, Herrmann A. 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