AI Article Synopsis
- - A 29-year-old man with chronic atopic dermatitis experienced fatigue, fever, and weight loss, leading to the discovery of a new heart murmur and skin complications during examination.
- - He was diagnosed with infective endocarditis caused by bacteria from his poorly controlled dermatitis, requiring treatment with antibiotics and surgery to repair the tricuspid valve.
- - This case highlights the unusual link between well-managed atopic dermatitis and serious systemic infections, emphasizing the need for effective treatment to prevent complications.
Article Abstract
A 29-year-old male, with chronic atopic dermatitis (AD), presented with a 2-week history of fatigue, pyrexia and weight loss. Examination showed eczematous patches with lichenified papules, erosions on the right shin and a new murmur. Blood cultures isolated methicillin-sensitive . Transthoracic echocardiography showed vegetation on the tricuspid valve (TV) that was adherent to the septal leaflet. He was treated for infective endocarditis, attributed to poorly controlled AD, with intravenous Flucloxacillin. Due to ongoing sepsis and pulmonary septic emboli, Clindamycin was added. He underwent TV repair; the septal leaflet was excised, and the remnant two leaflets were brought together with a ring. His patent foramen ovale was closed. His skin was treated with topical steroids and emollients. Right-sided endocarditis of an intact TV is uncommon in a non-intravenous drug user. Therefore, this novel case portrays the importance of aggressively managing AD as it is a risk factor for significant systemic infections.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376984 | PMC |
| http://dx.doi.org/10.1093/omcr/omaa045 | DOI Listing |
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