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| http://dx.doi.org/10.1111/apa.15498 | DOI Listing |
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The relationship between patient-reported and clinician-assessed outcome measures in Inclusion body myositis - insights from a retrospective cohort study.
Neuromuscul Disord
December 2024
School of Medicine, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University, Murdoch, Western Australia, Australia; Perron Institute of Neurological and Translational Sciences, Nedlands, Western Australia, Australia; Department of Neurology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
Inclusion body myositis (IBM) is an inflammatory myopathy, characterised by slow progression of weakness, skeletal muscle atrophy, and heterogeneous clinical presentation. This variability in disease progression and presentation complicates tracking of clinical progress and intervention response in clinical trials, presenting challenges in identifying reliable outcome measures. We aimed to identify the most useful suite of clinician-assessed and patient-reported outcome measures (PROMs) for use in clinical practice and trials from a selection of the most commonly used outcome measures in IBM.
View Article and Find Full Text PDFNeuromuscular Strategies in Dominant and Non-Dominant Legs in Dancers During Dynamic Balance Tasks.
J Dance Med Sci
January 2025
Frontier Research Institute of Convergence Sports Science, College of Educational Sciences, Yonsei University, Seoul, Korea.
Ballet-based dance training emphasizes the equal development of both legs. However, dancers often perceive differences between their legs during balance or landing. There still needs to be more consensus on the functional difference between dominant (D) and non-dominant legs (ND).
View Article and Find Full Text PDFNutritional Strategies for Enhancing Performance and Training Adaptation in Weightlifters.
Int J Mol Sci
December 2024
Institute of Health & Environment, Seoul National University, Seoul 08826, Republic of Korea.
Weightlifting demands explosive power and neuromuscular coordination in brief, repeated intervals. These physiological demands underscore the critical role of nutrition, not only in optimizing performance during competitions but also in supporting athletes' rigorous training adaptations and ensuring effective recovery between sessions. As weightlifters strive to enhance their performance, well-structured nutritional strategies are indispensable.
View Article and Find Full Text PDFEffect of Pilates Intervention on the Physical Conditioning of a Ballet Dancer: A Single Case Study.
J Chiropr Med
August 2024
Department of Physical Education, São Paulo State University, São Paulo, Brazil.
Objective: The purpose of this case study was to report the effect of an 8-week Pilates intervention on a ballet dancer's strength, balance, and endurance.
Clinical Features: A healthy 24-year-old ballet dancer (50 kg, 1.66 meters, 12 years of practice and who had no previous experience with Pilates) presented for care.
Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan.
Skelet Muscle
January 2025
Department of Molecular Physiology and Biophysics, and Department of Neurology, Howard Hughes Medical Institute, Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Background: Maintaining the connection between skeletal muscle fibers and the surrounding basement membrane is essential for muscle function. Dystroglycan (DG) serves as a basement membrane extracellular matrix (ECM) receptor in many cells, and is also expressed in the outward-facing membrane, or sarcolemma, of skeletal muscle fibers. DG is a transmembrane protein comprised of two subunits: alpha-DG (α-DG), which resides in the peripheral membrane, and beta-DG (β-DG), which spans the membrane to intracellular regions.
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