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Comparison of 2 portable human glucometers for the measurement of blood glucose concentration in White New Zealand rabbits. | LitMetric

Comparison of 2 portable human glucometers for the measurement of blood glucose concentration in White New Zealand rabbits.

J Vet Diagn Invest

Graduate Program in Animal Science (Silva, Costa, Sotomaior) and Undergraduate Program in Veterinary Medicine (Rotta), Pontifícia Universidade Católica do Paraná, Paraná, Brazil.

Published: September 2020

We compared measurements of blood glucose concentrations in 30 healthy adult White New Zealand rabbits using 2 commercial portable glucometers (PGM1 and PGM2) and a laboratory chemical analyzer. Results were analyzed with Pearson correlation, Passing-Bablok regression analysis, Bland-Altman analysis, and a modified error grid. Measurements with PGM1 were significantly correlated ( 0.37) with those obtained from the laboratory reference method (RM); Bland-Altman and Passing-Bablok analyses indicated no significant systematic or proportional differences (mean difference of -0.26, 95% CI of mean difference of -0.54 to 0.01, and LOA of -1.70 to 1.17); and error grid resulted in 100% of measurements in zone A. No significant correlation ( = -0.05) was detected between PGM2 and RM; Bland-Altman and Passing-Bablok analyses results indicated a mean difference of 2.14, 95% CI of mean difference of 1.67-2.60, and limit of agreement of -0.32 to 4.59, which overestimated blood glucose concentration, with 53% of glucose measurements in error grid zone A and 47% in zone B. PGM1 was considered accurate in normoglycemic rabbits, whereas the use of PGM2 could result in overestimations of glycemia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488964PMC
http://dx.doi.org/10.1177/1040638720946702DOI Listing

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