A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Attempt to read property "Count" on bool

Filename: helpers/my_audit_helper.php

Line Number: 3100

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Antimicrobial Activity of Extracts of Two Native Fruits of Chile: Arrayan () and Peumo (). | LitMetric

AI Article Synopsis

  • Arrayan and peumo fruits are used in Chilean traditional medicine, and a study analyzed their effectiveness against bacterial strains, including drug-resistant ones, focusing on their ability to inhibit bacterial viability and biofilm formation.* -
  • Arrayan extract was found to be more effective than peumo extract in reducing planktonic cell growth and in preventing bacterial adhesion, as well as inhibiting quorum sensing, particularly through autoinducer-2 communication.* -
  • The chemical analysis revealed that both extracts contain quercetin, with peumo also having additional phenolic compounds; the findings suggest their potential as natural antimicrobials for managing certain infections.*

Article Abstract

Arrayan and peumo fruits are commonly used in the traditional medicine of Chile. In this study, the concentration of the extracts halving the bacterial viability and biofilms formation and disruption of the drug-sensitive and drug-resistant strains of and was determined. The chemical composition of extracts was analyzed by high-resolution liquid chromatography coupled with mass spectrometry (U-HPLC/MS). The arrayan extract (Inhibitory concentration IC 0.35 ± 0.01 mg/mL) was more effective than peumo extract (IC 0.53 ± 0.02 mg/mL) in the inhibition of planktonic cells. Similarly, the arrayan extract was more effective in inhibiting the adhesion ( IC 0.23 ± 0.02 mg/mL, IC 0.29 ± 0.02 mg/mL) than peumo extracts ( IC 0.47 ± 0.03 mg/mL, IC 0.35 ± 0.01 mg/mL). Both extracts inhibited quorum sensing in a concentration-dependent manner, and the most significant was the autoinducer-2 type communication inhibition by arrayan extract. Both extracts also disrupted preformed biofilm of (arrayan IC 0.56 ± 0.04 mg/mL, peumo IC 0.59 ± 0.04 mg/mL). However, neither arrayan nor peumo extracts disrupted mature biofilm. U-HPLC/MS showed that both fruit extracts mainly possessed quercetin compounds; the peumo fruit extract also contained phenolic acids and phenylpropanoids. Our results suggested that both extracts could be used as natural antimicrobials for some skin and nosocomial infections.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459669PMC
http://dx.doi.org/10.3390/antibiotics9080444DOI Listing

Publication Analysis

Top Keywords

arrayan peumo
12
arrayan extract
12
002 mg/ml
12
extracts
9
035 001
8
mg/ml
8
001 mg/ml
8
mg/ml peumo
8
peumo extracts
8
extracts disrupted
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!