Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.
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http://dx.doi.org/10.1159/000510178 | DOI Listing |
Ann Gastroenterol Surg
January 2025
The Japanese Society of Gastroenterological Surgery Tokyo Japan.
Aim: The Japanese National Clinical Database, which covers more than 95% of the surgeries performed in Japan, is the largest nationwide database. This is the 2021 annual report of the Gastroenterological Section of the National Clinical Database, which aims to present the short-term outcomes of cases registered in 2021 and discuss significant changes and insights into gastroenterological surgeries observed over the decade.
Methods: We reviewed the data of patients registered in the National Clinical Database between 2012 and 2021.
Iran J Nurs Midwifery Res
November 2024
Exercise Physiology Research Center, Lifestyle Institute, Baqiyatallah University of Medical Sciences, Tehran, I.R. Iran.
Background: Recent evidence suggests a negative correlation between physical activity and the incidence and severity of noncommunicable chronic diseases like cardiovascular disease, diabetes, and respiratory infections. This study explores the potential influence of physical activity levels on the mortality rate and coronavirus disease (COVID-19) recovery.
Materials And Methods: This descriptive analytical cross-sectional study evaluated 175 Polymerase Chain Reaction (PCR)-confirmed COVID-19 patients admitted to Baqiyatallah Hospital.
Iran J Nurs Midwifery Res
November 2024
Department of Infectious Diseases, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: In patients with coronavirus disease 2019 (COVID-19), the incidence of delirium has been increased due to the nature of the disease and the specific protective protocols implemented to control the outbreak of this disease. The purpose of this study was to determine the effect of multidimensional nursing interventions on the incidence of delirium in patients with COVID-19.
Materials And Methods: A quasiexperimental study (preintervention, postintervention assessment) was conducted in168 patients (84 patients in each group) with COVID-19 admitted to the general wards of in , , between May and June 2021.
Mediators Inflamm
December 2024
Lung Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
The neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), derived neutrophil-to-lymphocyte ratio (dNLR), neutrophil-to-lymphocyte and platelet ratio (N/LP ratio), aggregate index of systemic inflammation (AISI), systemic inflammation response index (SIRI), and systemic inflammation index (SII) have emerged as noteworthy determinants in evaluating the severity and mortality prognosis of inflammatory diseases. In order to predict mortality rate, this study aimed to assess the impact of systemic inflammatory markers on both men and women who were admitted to the hospital due to SARS-CoV-2 infection. The laboratory parameters of the 2007 COVID-19 patients were analyzed in a retrospective study (men = 1145 and women = 862).
View Article and Find Full Text PDFHeliyon
December 2024
Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
Coronavirus disease 2019 (COVID-19) is a highly contagious viral disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It can manifest as mild to severe flu-like and non-flu-like symptoms and signs, which are associated with immune dysfunction and increased mortality. The findings from COVID-19 patients imply a link between immune system abnormalities such as impaired T-cell responses or cytokine imbalances and increased risk for worse clinical outcomes, which has not been fully understood.
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