Introduction: When severe intraventricular hemorrhage (IVH) casting in moyamoya disease (MMD) is mentioned, experts advocate not to evacuate the IVH in acute phase. However, the devastating outcomes derived from this empirical rule have not been addressed. Herein, we report two MMD cases undergoing obliteration of ruptured aneurysm and early complete aspiration of severe IVH casting, and showed good outcomes.
Presentation Of Cases: Case 1: A 55-year-old woman was admitted to our hospital. Her initial Glasgow Coma Scale (GCS) was 4 and a computerized tomography (CT) scan showed severe IVH. Cerebral angiography (CAG) revealed MMD and an aneurysm. Direct surgery was performed for the ruptured aneurysm, followed by endoscopic complete aspiration of residual IVH. The modified Rankin Scale (mRS) was 1 at discharge. Case 2: A 44-year-old woman was admitted to our hospital. Her initial GCS was 4 and the CT scan showed a severe IVH. CAG revealed MMD and an aneurysm. Transcatheter arterial embolization was carried out for the aneurysm, followed by endoscopic complete aspiration of the residual IVH. The mRS was 2 at discharge.
Discussion: Performing only external ventricular drainage in acute phase for such IVH casting is generally preferred way, however, there are no scientific date supporting this empirical rule. Early surgical removal of severe IVH casting is an approach for severe IVH casting in MMD.
Conclusion: Early aspiration of severe IVH casting is an option for managing MMD with critical intracranial pressure, and it has the potential to prevent poor outcomes in MMD patients with severe IVH.
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http://dx.doi.org/10.1016/j.ijscr.2020.07.021 | DOI Listing |
BMC Pediatr
January 2025
Department of Child Health, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 510623, Guangzhou, China.
Background: This study aimed to explore the risk factors for early intraventricular hemorrhage (IVH) in extremely low birth weight infants (ELBWIs) to provide guidance for early intervention, thereby improving survival rates and quality of life for these vulnerable infants.
Methods: A retrospective study was conducted on 205 ELBWIs admitted to the Women and Children's Medical Center of Guangzhou Medical University from January 2019 to December 2023. Standard head ultrasound screening (HUS) was used to assess the presence and severity of IVH on days 1-3 and 5-7 post-birth.
Neurosurgery
January 2025
Department of Neurosurgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Background And Objectives: Low-birth weight, premature infants often have severe intraventricular hemorrhage (IVH), which can result in posthemorrhagic hydrocephalus (PHH), sometimes requiring cerebrospinal fluid diversion. Initial temporizing management of PHH includes placement of a ventriculosubgaleal shunt (VSGS) or ventricular access device (VAD). Studies have found similar permanent shunt conversion rates between VSGS and VAD but were limited by sample scope and size.
View Article and Find Full Text PDFJAMA Pediatr
December 2024
Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Importance: Intraventricular hemorrhage (IVH) has been described to typically occur during the early hours of life (HOL); however, the exact time of onset is still unknown.
Objective: To investigate the temporal distribution of IVH reported in very preterm neonates.
Data Sources: PubMed, Embase, Cochrane Library, and Web of Science were searched on May 9, 2024.
JAMA Netw Open
January 2025
Population Policy and Practice, Great Ormond Street UCL Institute of Child Health, London, United Kingdom.
Importance: Intraventricular hemorrhage (IVH) has proven to be a challenging and enduring complication of prematurity. However, its association with neurodevelopment across the spectrum of IVH severity, independent of prematurity, and in the context of contemporary care remains uncertain.
Objective: To evaluate national trends in IVH diagnosis and the association with survival and neurodevelopmental outcomes at 2 years of age.
Pediatr Res
December 2024
Department of Neurological Surgery, Ohio State University Medical Center, Columbus, OH, USA.
Background: Post-hemorrhagic hydrocephalus (PHH) is a severe complication in premature infants following intraventricular hemorrhage (IVH). It is characterized by abnormal cerebrospinal fluid (CSF) accumulation, disrupted CSF dynamics, and elevated intracranial pressure (ICP), leading to significant neurological impairments.
Objective: This review provides an overview of recent molecular insights into the pathophysiology of PHH and evaluates emerging therapeutic approaches aimed at addressing its underlying mechanisms.
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