The present hypothesis suggests an innovative therapeutic strategy to cease Covid 19 infection. It is based on the inhibition of Spike glycoprotein and ACE-2 receptor interaction that provides the entry of virus in human host cells, by targeting the S protein with a recombinant molecule made of the ACE-2 receptor ectodomain and an opsonin, the formed complex would enhance its phagocytosis.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358758 | PMC |
http://dx.doi.org/10.1016/j.mehy.2020.110108 | DOI Listing |
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