Ligulaveitnoid A, a new phenylpropanoid from rhizomes and roots of .

Nat Prod Res

Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, China.

Published: February 2022

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Article Abstract

A new phenylpropanoid, ligulaveitnoid A (), along with four known compounds, ()-2,3-dihydroconiferyl -coumarate (), dihydroconiferyl ferulate (), 4-hydroxy-3-methoxybenzaldehyde () and ()--coumaric acid () were isolated from rhizomes and roots of . All the structures of compounds were identified by the interpretation of their spectroscopic data and comparison with those reported in the literature. The anti-inflammatory activity of the isolates was examined for their inhibitory effects on LPS-induced NO production in macrophage RAW264.7 cells. Among them, compound showed strong inhibitory activities towards the LPS-induced NO production in macrophage RAW264.7 cells with IC value of 8.0 M.

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http://dx.doi.org/10.1080/14786419.2020.1798663DOI Listing

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