Patient disruption during dental visits can impede treatment and may result in invasive approaches to care. The current study evaluated the efficacy of graduated exposure with and without extinction to decrease disruption during dental treatment for 4 young men with autism spectrum disorder (ASD). Modified functional analyses confirmed that disruption was maintained by escape from dental demands for all four young men. Initial treatment consisted of graduated exposure, whereby exam steps were initially removed and then gradually reintroduced as disruption remained low; throughout this phase, disruption resulted in a break from the exam. During the subsequent treatment phase, graduated exposure procedures continued and extinction for disruption was added. Graduated exposure alone did not result in sufficient treatment effects; however, the addition of extinction resulted in greater reductions in disruption and increases in exam completion for all 4 young men, and treatment effects generalized to a dental clinic setting.
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http://dx.doi.org/10.1002/jaba.747 | DOI Listing |
Anticancer Res
January 2025
Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan.
Background/aim: This study aimed to predict the optimal timing for adaptive radiation therapy (ART) using two-dimensional X-ray image-based water equivalent thickness (2DWET).
Patients And Methods: Forty patients with oropharyngeal and hypopharyngeal cancer underwent Computed Tomography (CT) rescanning during treatment. An adaptive score (AS) was proposed to guide ART decisions based on changes in four dose indices: target coverage, spinal cord dose, parotid gland dose, and over-dose volume.
Environ Int
December 2024
National Institute for Minamata Disease, Minamata, Kumamoto 867-0008, Japan.
Minamata disease, a severe neurological disorder identified in Japan in 1956, results from methylmercury (MeHg) intoxication in humans due to environmental contamination. Before MeHg was recognized as the cause, selenium (Se) was suspected of being the potential cause owing to elevated Se levels in patients' organs. Subsequent animal studies indicated that Se mitigates MeHg toxicity; however, its role in Minamata disease remains unexplored.
View Article and Find Full Text PDFBiom J
February 2025
Institute of Health and Environment, Seoul National University, Seoul, Republic of Korea.
Epidemiological research aims to investigate how multiple exposures affect health outcomes of interest, but observational studies often suffer from biases caused by unmeasured confounders. In this study, we develop a novel sensitivity model to investigate the effect of correlated multiple exposures on the continuous health outcomes of interest. The proposed sensitivity analysis is model-agnostic and can be applied to any machine learning algorithm.
View Article and Find Full Text PDFCommunity Dent Oral Epidemiol
December 2024
Faculty of Dentistry, Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Objective: To examine the association between the lifetime utilisation of dental services and dental caries experience in mixed dentition among adolescents participating in the 2004 Pelotas Birth Cohort, Southern Brazil.
Methods: This longitudinal study analysed a sample of 996 adolescents aged 12-13 years. Dental caries experience and untreated dental caries were the outcomes, assessed by the mean of decayed, missed and filled in deciduous (dmfs index) and in permanent (DMFS index) teeth, based on World Health Organization criteria.
Environ Sci Pollut Res Int
December 2024
Department of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, 163 Horria Ave. El-Shatby, P.O. Box 832, Alexandria, Egypt.
Phenol is a highly concerning pollutant in petrochemical industrial wastewater. It is extremely poisonous, carcinogenic, and persistent, therefore, it bioaccumulates in the food chain reaching humans, where it causes acute irritation to the skin, eyes, and respiratory tract, as well as chronic effects on the liver, kidneys, and nervous system. It spills or leaks easily into surface water or groundwater sources, leading to the creation of other harmful substituted compounds.
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