Empirical results hinge on analytical decisions that are defensible, arbitrary and motivated. These decisions probably introduce bias (towards the narrative put forward by the authors), and they certainly involve variability not reflected by standard errors. To address this source of noise and bias, we introduce specification curve analysis, which consists of three steps: (1) identifying the set of theoretically justified, statistically valid and non-redundant specifications; (2) displaying the results graphically, allowing readers to identify consequential specifications decisions; and (3) conducting joint inference across all specifications. We illustrate the use of this technique by applying it to three findings from two different papers, one investigating discrimination based on distinctively Black names, the other investigating the effect of assigning female versus male names to hurricanes. Specification curve analysis reveals that one finding is robust, one is weak and one is not robust at all.
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http://dx.doi.org/10.1038/s41562-020-0912-z | DOI Listing |
Scand J Urol
January 2025
Department of Urology, Odense University Hospital, Odense, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Objective: Early and accurate diagnosis of prostate cancer (PC) is crucial for effective treatment. Diagnosing clinically insignificant cancers can lead to overdiagnosis and overtreatment, highlighting the importance of accurately selecting patients for further evaluation based on improved risk prediction tools. Novel biomarkers offer promise for enhancing this diagnostic process.
View Article and Find Full Text PDFJ Rehabil Assist Technol Eng
January 2025
University of Regina, Regina, SK, Canada.
Regular use of standardized observational tools to assess nonverbal pain behaviors results in improved pain care for older adults with severe dementia. While frequent monitoring of pain behaviors in long-term care (LTC) is constrained by resource limitations, computer vision technology has the potential to mitigate these challenges. A computerized algorithm designed to assess pain behavior in older adults with and without dementia was recently developed and validated using video recordings.
View Article and Find Full Text PDFFront Nutr
December 2024
Department of Medical Oncology, Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Introduction: The relationship between physical activity (PA) and nutritional status on the prognosis of cancer survivors remains underexplored. We aimed to investigate the combined effects of PA and Geriatric Nutritional Risk Index (GNRI) on prognostic assessment of survival outcomes in US cancer survivors.
Methods: 2,619 subjects were screened from the National Health and Nutrition Examination Survey (NHANES) database from 1999 to 2018.
Risk Manag Healthc Policy
January 2025
Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, New Taipei City, 235603, Taiwan.
Purpose: As HF progresses into advanced HF, patients experience a poor quality of life, distressing symptoms, intensive care use, social distress, and eventual hospital death. We aimed to investigate the relationship between morality and potential prognostic factors among in-patient and emergency patients with HF.
Patients And Methods: A case series study: Data are collected from in-hospital and emergency care patients from 2014 to 2021, including their international classification of disease at admission, and laboratory data such as blood count, liver and renal functions, lipid profile, and other biochemistry from the hospital's electrical medical records.
Int J Nurs Stud Adv
June 2025
Los Angeles General Medical Center, Los Angeles, CA, United States.
Background: There is a lack of high-quality evidence to support the recommendation of an instrument to screen emergency department patients for their risk for violence.
Objective: To demonstrate the content and predictive validity and reliability of the novel Risk for Violence Screening Tool to identify patients at risk for violence.
Design And Setting: This retrospective risk screening study was conducted at a 100-bed emergency department in an urban, academic, safety net trauma center in Southern California.
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