Aim: Obesity is a leading cause of preventable death worldwide and is increasing in both adults and children. Bariatric surgery is the most effective treatment for this condition and its related comorbidities. We aimed to evaluate the effectiveness of different staple line reinforcement techniques on staple line reinforcement through bursting pressures.
Methods: Different stapler line strengthening techniques were performed on resected stomach patterns of 48 patients. The patients were enrolled prospectively into 4 groups according to surgeons preferred type of staple line reinforcement. Data concerning patient demographic variables, surgical parameters, postoperative complications, postoperative readmissions, burst pressure and burst point were collected. None of the obese patients were excluded from this study.
Results: There were no statistically significant differences in the characteristics of the groups. The number of staple cartridges fired and the linearity of the staple line were similar in all groups, (p 0.524-0.265). However, there were significant differences in the burst pressure measurements in groups I, II, IIIand IV (p .001). In all groups, the burst point on the staple line of resected stomach was most commonly in the fundus section.
Conclusions: We believe that the burst pressure in Fibrin sealant group is significantly higher and that fibrin glue can be effective in preventing stapler line leakage. We believe that more advanced studies are needed.
Key Words: Fibrin Sealant, Leakage, Reinforcement.
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In surgery for acute type A aortic dissection, controlling bleeding from the posterior wall of the proximal anastomosis is particularly challenging. To address this, we use the "reversed turn-up technique." For the reinforcement of the proximal aortic stump, Teflon felt strips were placed inside and outside the suture line with 4-0 polypropylene continuous transverse mattress sutures, and BioGlue was applied to the false lumen.
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg
December 2024
Department of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba, 260-8670, Japan.
Background: Air leakage during pulmonary resection is a major complication in thoracic surgery. It frequently occurs at sites of adhesion dissection, due to lung manipulation, and along the staple lines of automatic suturing devices, particularly in cases of pulmonary fragility such as those of emphysema and interstitial pneumonia. Persistent postoperative air leakage prolongs chest tube indwelling and extends hospitalization time.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Université de Bordeaux, CBMN UMR5248, IECB, 2, rue Robert Escarpit, 33607, PESSAC, FRANCE.
Peptide stapling has emerged as a versatile approach in drug discovery to reinforce secondary structure elements especially α-helices and improve properties of linear bioactive peptides. Inspired by the prevalence of arginine in protein-protein and protein-DNA interfaces, we investigated guanidinium-stapling as a means to constrain helical peptides. Guanidinium stapling was readily achieved on solid support, utilizing two orthogonally protected lysine or unatural α-amino acid residues with an amino function.
View Article and Find Full Text PDFTransl Androl Urol
November 2024
Division of Urology, Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Background: There is limited data within the urologic literature regarding bowel complications and leak rates following surgery requiring ileocolic anastomoses such as right colon pouch (RCP) and continent cutaneous ileocecocystoplasty (CCIC). We aimed to establish ileocolic anastomotic leak rates in urologic reconstructive surgery and determine bowel-related complications following RCP and CCIC surgeries.
Methods: We reviewed adult patients who underwent RCP or CCIC (2010-2022), investigating patient characteristics, perioperative variables, and outcomes.
Cureus
November 2024
Department of Orthopedics, Krishna Vishwa Vidyapeeth (Deemed to be University), Satara, IND.
Patellar fractures can lead to extensor mechanism dysfunction if not repaired properly, impacting knee function and mobility, and this complication can be challenging to manage, especially in cases where previous surgical interventions have failed. The aim of this study was to evaluate the functional outcome of the salvaged extensor mechanism in patella fracture non-union using Krakow sutures in a 61-year-old female patient who presented with knee pain, reduced flexion, and a 40-degree extension lag after two previous patellar fracture surgeries using tension band wiring resulted in non-union. Despite rehabilitation attempts, her knee function remained compromised.
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